OBJECTIVES: To summarize published data on the clinical and economic burden,
epidemiology, antimicrobial resistance levels, serotype prevalence, and prevention …

We performed a prospective, international, observational study of 844 hospitalized patients
with blood cultures positive for Streptococcus pneumoniae. Fifteen percent of isolates had in …

A successful therapy of community-acquired pneumonia requires appropriate empirical
antimicrobial therapy. Etiology and antimicrobial susceptibility of major pathogens of …

In the current era of multidrug-resistant organisms, the clinical spectrum of Streptococcus
pneumoniae infection remains unclear, especially in immunosuppressed patients with …

ABSTRACT A nationwide surveillance study was undertaken to monitor antimicrobial
resistance among clinical isolates of Streptococcus pneumoniae in Korea, with a special …

High-dose oral amoxicillin (3 g/day) is the recommended empirical outpatient treatment of
community-acquired pneumonia (CAP) in many European guidelines. To investigate the …

The objective of the case-control study presented here was to examine the risk factors for
macrolide-resistant Streptococcus pneumoniae. As part of a 44-center US surveillance …

The clinical impact of antimicrobial resistance on the outcome of pneumococcal bacteraemia
has remained unclear. This study aimed to evaluate risk factors for mortality and determine …

Background: Pneumococcal disease is a major global cause of morbidity and mortality. This
study evaluated risk factors for mortality in children with pneumococcal meningitis and other …

Pathogens implicated in community-acquired respiratory tract infections are becoming
increasingly resistant to antibacterial therapies. Thus, there is an urgent need for new agents …