Origins of HIV and the AIDS pandemic

PM Sharp, BH Hahn - Cold Spring …, 2011 - perspectivesinmedicine.cshlp.org
Acquired immunodeficiency syndrome (AIDS) of humans is caused by two lentiviruses,
human immunodeficiency viruses types 1 and 2 (HIV-1 and HIV-2). Here, we describe the …

Why primate models matter

KA Phillips, KL Bales, JP Capitanio… - American journal of …, 2014 - Wiley Online Library
Research involving nonhuman primates (NHPs) has played a vital role in many of the
medical and scientific advances of the past century. NHPs are used because of their …

Evasion of cGAS and TRIM5 defines pandemic HIV

L Zuliani-Alvarez, ML Govasli, J Rasaiyaah… - Nature …, 2022 - nature.com
Of the 13 known independent zoonoses of simian immunodeficiency viruses to humans,
only one, leading to human immunodeficiency virus (HIV) type 1 (M) has become pandemic …

HIV-1 capsid-cyclophilin interactions determine nuclear import pathway, integration targeting and replication efficiency

T Schaller, KE Ocwieja, J Rasaiyaah, AJ Price… - PLoS …, 2011 - journals.plos.org
Lentiviruses such as HIV-1 traverse nuclear pore complexes (NPC) and infect terminally
differentiated non-dividing cells, but how they do this is unclear. The cytoplasmic NPC …

The evolution of HIV-1 and the origin of AIDS

PM Sharp, BH Hahn - … of the Royal Society B: Biological …, 2010 - royalsocietypublishing.org
The major cause of acquired immune deficiency syndrome (AIDS) is human
immunodeficiency virus type 1 (HIV-1). We have been using evolutionary comparisons to …

Hiv-2 molecular epidemiology

B Visseaux, F Damond, S Matheron… - Infection, Genetics and …, 2016 - Elsevier
Abstract The Simian Immunodeficiency Virus of sooty mangabeys (SIVsmm) has been
revealed to be at the origin of Human Immunodeficiency Virus type 2 (HIV-2) in humans …

Mechanisms of pathogenesis induced by bovine leukemia virus as a model for human T-cell leukemia virus

Y Aida, H Murakami, M Takahashi… - Frontiers in …, 2013 - frontiersin.org
Bovine leukemia virus (BLV) and human T-cell leukemia virus type 1 (HTLV-1) make up a
unique retrovirus family. Both viruses induce chronic lymphoproliferative diseases with BLV …

Simian Immunodeficiency Virus Infection in Free-Ranging Sooty Mangabeys (Cercocebus atys atys) from the Taï Forest, Côte d'Ivoire: Implications for the Origin of …

ML Santiago, F Range, BF Keele, Y Li, E Bailes… - Journal of …, 2005 - Am Soc Microbiol
Simian immunodeficiency virus of sooty mangabeys (SIVsmm) is recognized as the
progenitor of human immunodeficiency virus type 2 (HIV-2) and has been transmitted to …

Key viral adaptations preceding the AIDS pandemic

D Sauter, F Kirchhoff - Cell host & microbe, 2019 - cell.com
HIV, the causative agent of AIDS, has a complex evolutionary history involving several cross-
species transmissions and recombination events as well as changes in the repertoire and …

[图书][B] Evolution in health and disease

SC Stearns, JC Koella - 2008 - books.google.com
In this fully revised and updated edition, the editors have integrated a completely new set of
contributions from the leading researchers in the field to describe the latest research in …