Association of proton pump inhibitors with risk of dementia: a pharmacoepidemiological claims data analysis

W Gomm, K von Holt, F Thomé, K Broich… - JAMA …, 2016 - jamanetwork.com
Importance Medications that influence the risk of dementia in the elderly can be relevant for
dementia prevention. Proton pump inhibitors (PPIs) are widely used for the treatment of …

Does the long-term administration of proton pump inhibitors increase the risk of adverse cardiovascular outcomes? A ChatGPT powered umbrella review

E Teperikidis, A Boulmpou, V Potoupni, S Kundu… - Acta …, 2023 - Taylor & Francis
Abstract Background Proton pump inhibitors (PPIs) are commonly prescribed for the
treatment of acid-related disorders. In the context of coronary artery disease (CAD), PPIs are …

[HTML][HTML] Impact of proton-pump inhibitors on the efficacy of immune checkpoint inhibitors in non-small cell lung cancer: A systematic review and meta-analysis

S Dar, N Merza, M Rahim, A Qatani… - Annals of Medicine and …, 2022 - Elsevier
Introduction Immune checkpoint inhibitors (ICI) is a rapidly evolving treatment modality for
stage IV non-small cell lung cancer (NSCLC). Concomitant proton pump inhibitor (PPI) use …

Community acquired pneumonia incidence before and after proton pump inhibitor prescription: population based study

F Othman, CJ Crooks, TR Card - bmj, 2016 - bmj.com
Objective To examine the risk of community acquired pneumonia before and after
prescription of proton pump inhibitor (PPI) and assess whether unmeasured confounding …

No association between proton pump inhibitor use and risk of dementia: Evidence from a meta‐analysis

S Hussain, A Singh, S Zameer… - Journal of …, 2020 - Wiley Online Library
Background and Aim A growing body of literature suggests the association between
dementia risk and proton pump inhibitor (PPI) use. Therefore, we aimed to investigate the …

Long‐term use of proton pump inhibitors and prevalence of disease‐and drug‐related reasons for gastroprotection—a cross‐sectional population‐based study

SM Wallerstedt, J Fastbom, J Linke… - … and drug safety, 2017 - Wiley Online Library
Purpose To analyse the prevalence of long‐term use of proton pump inhibitors (PPI) with
respect to underlying diseases and drugs, and to find predictors for such treatment when an …

The association between proton pump inhibitors use and clinical outcome of patients receiving immune checkpoint inhibitors therapy

M Li, C Zeng, J Yao, Y Ge, G An - International Immunopharmacology, 2020 - Elsevier
Background The gut microbiome can mediate the efficacy of immune checkpoint inhibitors
(ICI). Meanwhile, proton pump inhibitors (PPI) can modulate the gut microbiome …

National trends in prescription proton pump inhibitor use and expenditure in the United States in 2002-2017

AU Mishuk, L Chen, P Gaillard, S Westrick… - Journal of the American …, 2021 - Elsevier
Abstract Objectives In the United States, proton pump inhibitors (PPIs) are one of the most
commonly prescribed classes of drugs, but contemporary data on national-level utilization …

Proton pump inhibitor use does not increase dementia and Alzheimer's disease risk: An updated meta-analysis of published studies involving 642305 patients

YQ Song, Y Li, SL Zhang, J Gao, SY Feng - PloS one, 2019 - journals.plos.org
Recent studies have indicated an increased risk of dementia and Alzheimer's disease (AD)
among people who consume proton pump inhibitors (PPIs), but the results of those studies …

Proton pump inhibitors and dementia risk: Evidence from a cohort study using linked routinely collected national health data in Wales, UK

R Cooksey, J Kennedy, MS Dennis, V Escott-Price… - PloS one, 2020 - journals.plos.org
Objectives Proton pump inhibitors (PPIs) are commonly prescribed for prevention and
treatment of gastrointestinal conditions or for gastroprotection from other drugs. Research …