Human‐derived tumor models are essential for preclinical development of new anticancer
drug entities. Generating animal models bearing tumors of human origin, such as patient …

Objective A preclinical study was designed to evaluate the effects of adoptively transferred
cytokine-induced killer (CIK) cells on colorectal adenocarcinoma. Methods Forty NOG mice …

Abstract Severely immunocompromised NOD. Cg‐Prkdc scid Il2rg tm1Sug (NOG) mice are
among the ideal animal recipients for generation of human cancer models. Transplantation …

Background: Xenogeneic graft-versus-host disease (xGvHD) is an inevitable confounder of
preclinical evaluation of adoptive immunotherapies on tumor-bearing immunodeficient …

Background Natural killer (NK) cell therapy has been shown to be effective in the treatment
of some cancers. However, the effects of this adoptive immunotherapy have not been …