Neurodevelopmental abnormalities and congenital heart disease: insights into altered brain maturation

PD Morton, N Ishibashi, RA Jonas - Circulation research, 2017 - Am Heart Assoc
In the past 2 decades, it has become evident that individuals born with congenital heart
disease (CHD) are at risk of developing life-long neurological deficits. Multifactorial risk …

Brain injury and neurodevelopmental outcome in congenital heart disease: a systematic review

MJ Mebius, EMW Kooi, CM Bilardo, AF Bos - Pediatrics, 2017 - publications.aap.org
OBJECTIVE: To assess the association between prenatal and postnatal preoperative
cerebral findings and NDO in infants with CHD who require corrective or palliative surgery …

Food and Drug Administration warning on anesthesia and brain development: implications for obstetric and fetal surgery

OA Olutoye, BW Baker, MA Belfort… - American journal of …, 2018 - Elsevier
There has been growing concern about the detrimental effects of certain anesthetic agents
on the developing brain. Preclinical studies in small animal models as well as nonhuman …

Congenital heart disease and neurodevelopment: clinical manifestations, genetics, mechanisms, and implications

SN Nattel, L Adrianzen, EC Kessler… - Canadian Journal of …, 2017 - Elsevier
Children with congenital heart disease (CHD) are at increased risk of neurodevelopmental
disorders (NDDs) and psychiatric conditions. These include cognitive, adaptive, motor …

Prevalence of prenatal brain abnormalities in fetuses with congenital heart disease: a systematic review

A Khalil, S Bennet, B Thilaganathan… - … in Obstetrics & …, 2016 - Wiley Online Library
Objectives Studies have shown an association between congenital heart defects (CHDs)
and postnatal brain abnormalities and neurodevelopmental delay. Recent evidence …

Longitudinal changes in fetal biometry and cerebroplacental hemodynamics in fetuses with congenital heart disease

A Ruiz, M Cruz‐Lemini, N Masoller… - … in Obstetrics & …, 2017 - Wiley Online Library
Objectives To determine the longitudinal behavior of fetal biometric measures and
cerebroplacental hemodynamics throughout gestation in fetuses with congenital heart …

Magnetic resonance spectroscopy of brain metabolism in fetuses with congenital heart disease

NN Andescavage, S Pradhan, AC Gimovsky… - Journal of the American …, 2023 - jacc.org
Background Congenital heart disease (CHD) remains a significant risk factor for neurologic
injury because altered fetal hemodynamics may be unable to support typical brain …

Neuroimaging, cardiovascular physiology, and functional outcomes in infants with congenital heart disease

NHP Claessens, CJ Kelly, SJ Counsell… - … Medicine & Child …, 2017 - Wiley Online Library
This review integrates data on brain dysmaturation and acquired brain injury using fetal and
neonatal magnetic resonance imaging (MRI), including the contribution of cardiovascular …

Individualized brain development and cognitive outcome in infants with congenital heart disease

AF Bonthrone, R Dimitrova, A Chew… - Brain …, 2021 - academic.oup.com
Infants with congenital heart disease are at risk of neurodevelopmental impairments, the
origins of which are currently unclear. This study aimed to characterize the relationship …

Fetal echocardiography for planning perinatal and delivery room care of neonates with congenital heart disease

L Sanapo, JD Pruetz, M Słodki, MB Goens… - …, 2017 - Wiley Online Library
Fetal echocardiography facilitates the prenatal diagnosis of infants with congenital heart
disease (CHD) and through sequential examinations, allows assessment of fetal …