Dual/Multi-responsive fluorogenic probes for multiple analytes in mitochondria: From design to applications

J Guo, B Fang, H Bai, L Wang, B Peng, XJ Qin… - TrAC Trends in …, 2022 - Elsevier
As the" powerhouse" of the cells, mitochondria participate in numerous energy metabolism
processes. Abnormal structure and function of mitochondria will affect the activities of living …

The Ugi three‐component reaction; a valuable tool in modern organic synthesis

NP Tripolitsiotis, M Thomaidi… - European Journal of …, 2020 - Wiley Online Library
The Ugi three component reaction (U‐3CR) is a variation of the famous Ugi reaction,
discovered almost 60 years ago. Today it is somehow neglected, compared to the classical …

Preserving Retinal Structure and Function with the Novel Nitroxide Antioxidant, DCTEIO

CL Rayner, SE Bottle, AP Martyn, NL Barnett - Neurochemical Research, 2023 - Springer
Oxidative stress is a major contributor to progressive neurodegenerative disease and may
be a key target for the development of novel preventative and therapeutic strategies …

Defect-rich titanium nitride nanoparticle with high microwave-acoustic conversion efficiency for thermoacoustic imaging-guided deep tumor therapy

Z Wu, F Zeng, L Zhang, S Zhao, L Wu, H Qin, D Xing - Nano Research, 2021 - Springer
Pulse microwave excite thermoacoustic (TA) Shockwave to destroy tumor cells in situ. This
has promising applications for precise tumor therapy in deep tissue. Nanoparticle (NP) with …

Synthesis, mitochondrial localization of fluorescent derivatives of cinnamamide as anticancer agents

K Yang, Y Li, Q Tang, L Zheng, D He - European Journal of Medicinal …, 2019 - Elsevier
Mitochondria are considered as a therapeutic target for new drug design toward all kinds of
cancer. Hence in order to enhance the dosage in mitochondrial fraction of cinnamamides …

Design of a prodrug photocage for cancer cells detection and anticancer drug release

Q Shao, F Zhang, C Li, Y Yang, S Liu, G Chen, B Fan - Talanta, 2024 - Elsevier
Developing probes for simultaneous diagnosis and killing of cancer cells is crucial, yet
challenging. This article presents the design and synthesis of a novel Rhodamine B …

Diastereoselective synthesis of multisubstituted isoindolines via sequential Ugi and aza-Michael addition reaction

ZR Guan, Q Wan, MW Ding - Tetrahedron, 2019 - Elsevier
A new efficient and diastereoselective synthesis of multisubstituted isoindolines with two
stereogenic centers via sequential Ugi/aza-Michael addition reaction was developed. Ugi …

Synthesis and application of stable nitroxide free radicals fused with Carbocycles and heterocycles

B Bognár, G Úr, C Sár, OH Hankovszky… - Current Organic …, 2019 - ingentaconnect.com
Stable nitroxide free radicals have traditionally been associated with 2, 2, 6, 6-
tetramethylpiperidine-1-oxyl (TEMPO) or its 4-substituted derivatives as relatively …

Visible light activated benzimidazolequinone alkoxyamines of 1, 1, 3, 3‐tetramethylisoindolin‐2‐yloxyl (TMIO)

P Kielty, BA Chalmers, P Farràs… - European Journal of …, 2021 - Wiley Online Library
Abstract 1, 1, 3, 3‐Tetramethylisoindolin‐2‐yloxyl (TMIO) is a well‐known stable 2, 3‐
dihydroisoindoline aminoxyl radical, which is thermally generated (at> 100° C) from …

Synthesis of Anti-oxidant Steroids by Hybridisation with Nitroxides

CP Soltau, NE Weir, AP Martyn, SE Bottle - Synthesis, 2024 - thieme-connect.com
Steroidal–nitroxide hybrid molecules and non-radical controls were synthesised in good
yields using simple carbodiimide coupling. An unexpected product arose from reactions …