Antiphospholipid syndrome: advances in diagnosis, pathogenesis, and management

JS Knight, DW Branch, TL Ortel - bmj, 2023 - bmj.com
Antiphospholipid syndrome (APS) is a thrombo-inflammatory disease propelled by
circulating autoantibodies that recognize cell surface phospholipids and phospholipid …

Diagnosis and management of cerebral venous thrombosis: a Scientific Statement from the American Heart Association

G Saposnik, C Bushnell, JM Coutinho, TS Field… - Stroke, 2024 - Am Heart Assoc
Cerebral venous thrombosis accounts for 0.5% to 3% of all strokes. The most vulnerable
populations include young individuals, women of reproductive age, and patients with a …

Direct oral anticoagulants vs vitamin K antagonists in patients with antiphospholipid syndromes: meta-analysis of randomized trials

CD Khairani, A Bejjani, G Piazza, D Jimenez… - Journal of the American …, 2023 - jacc.org
Background The efficacy and safety of direct oral anticoagulants (DOACs) for patients with
thrombotic antiphospholipid syndrome remain controversial. Objectives The authors …

2024 guideline for the primary prevention of stroke: a guideline from the American Heart Association/American Stroke Association

C Bushnell, WN Kernan, AZ Sharrief, S Chaturvedi… - Stroke, 2024 - ahajournals.org
AIM: The “2024 Guideline for the Primary Prevention of Stroke” replaces the 2014
“Guidelines for the Primary Prevention of Stroke.” This updated guideline is intended to be a …

Antiphospholipid syndrome management: a 2023 update and practical algorithm-based approach

A Ambati, JS Knight, Y Zuo - Current opinion in rheumatology, 2023 - journals.lww.com
Although the knowledge of APS pathogenesis has grown in recent years, the management
principles and strategies are largely unchanged. There is an unmet need for evaluating …

[PDF][PDF] Guidelines on the investigation and management of antiphospholipid syndrome

DJ Arachchillage, S Platton, K Hickey, J Chu… - Br J …, 2024 - cancer-networks.com
Review of the guideline followed the standard BSH guidelines procedure. Following review
of the draft guideline by the BSH Haemostasis and Thrombosis Task Force and the BSH …

Anticoagulant therapy in patients with antiphospholipid syndrome

M Capecchi, M Abbattista, A Ciavarella, M Uhr… - Journal of clinical …, 2022 - mdpi.com
Antiphospholipid syndrome (APS) is a systemic autoimmune disease characterized by the
persistent positivity of antiphospholipid antibodies (aPLA) together with thrombosis or …

[HTML][HTML] Survey on antiphospholipid syndrome diagnosis and antithrombotic treatment in patients with ischemic stroke, other brain ischemic injury, or arterial …

H Cohen, DJ Werring, A Chandratheva, P Mittal… - Journal of Thrombosis …, 2023 - Elsevier
Background The optimal strategy for diagnosis and antithrombotic treatment of patients with
antiphospholipid syndrome (APS)–associated acute ischemic stroke (AIS), transient …

Factor XI inhibitors for the prevention of cardiovascular disease: A new therapeutic approach on the horizon?

D Santagata, MP Donadini, W Ageno - Blood Reviews, 2023 - Elsevier
Anticoagulant drugs that are currently used to prevent and/or treat thrombosis have some
limitations that hinder their ability to meet specific clinical requirements. While these drugs …

Dilemmas in the diagnosis and management of antiphospholipid syndrome

JE Manning, DJ Arachchillage - Journal of Thrombosis and Haemostasis, 2024 - Elsevier
Antiphospholipid syndrome (APS) is characterized by thrombosis (which may be venous,
arterial, or microvascular) and/or pregnancy morbidity in association with persistently …