Role of vascular endothelial growth factor (VEGF) in human embryo implantation: clinical implications

X Guo, H Yi, TC Li, Y Wang, H Wang, X Chen - Biomolecules, 2021 - mdpi.com
Vascular endothelial growth factor (VEGF) is a well-known angiogenic factor that plays a
critical role in various physiological and pathological processes. VEGF also contributes to …

The constructive and destructive impact of autophagy on both genders' reproducibility, a comprehensive review

M Samare-Najaf, A Neisy, A Samareh, D Moghadam… - Autophagy, 2023 - Taylor & Francis
Reproduction is characterized by a series of massive renovations at molecular, cellular, and
tissue levels. Recent studies have strongly tended to reveal the involvement of basic …

[HTML][HTML] Insight of autophagy in spontaneous miscarriage

XY Qin, HH Shen, WJ Zhou, J Mei, H Lu… - … journal of biological …, 2022 - ncbi.nlm.nih.gov
In some cases of spontaneous miscarriage (SM), the exact etiology cannot be determined.
Autophagy, which is responsible for cellular survival under stress conditions, has also been …

LncRNA H19 Aggravates Intervertebral Disc Degeneration by Promoting the Autophagy and Apoptosis of Nucleus Pulposus Cells Through the miR-139/CXCR4/NF …

Z Sun, X Tang, H Wang, H Sun, P Chu… - Stem cells and …, 2021 - liebertpub.com
The etiology of lumbocrural pain is closely related to intervertebral disc degeneration (IDD).
Long noncoding RNAs (lncRNAs) serve crucial roles in IDD progression. This study …

Ruminant conceptus-maternal interactions: interferon-tau and beyond

DJ Mathew, KD Peterson, LK Senn… - Journal of Animal …, 2022 - academic.oup.com
Embryonic or fetal loss in cattle is associated with problems that occur during oocyte
maturation, early embryonic development, conceptus elongation, maternal recognition of …

[HTML][HTML] Maternal CXCR4 deletion results in placental defects and pregnancy loss mediated by immune dysregulation

F Lyu, C Burzynski, Y yuan Fang, A Tal, AY Chen… - JCI insight, 2023 - ncbi.nlm.nih.gov
CXCR4 is a key regulator of the development of NK cells and DCs, both of which play an
important role in early placental development and immune tolerance at the maternal-fetal …

Toward understanding the role of the interstitial tissue architects: Possible functions of telocytes in the male gonad

P Pawlicki, B Yurdakok-Dikmen, W Tworzydlo… - Theriogenology, 2024 - Elsevier
Telocytes represent a relatively recently discovered population of interstitial cells with a
unique morphological structure that distinguishes them from other neighboring cells …

Ruminant placental adaptation in early maternal undernutrition: An Overview

P Toschi, M Baratta - Frontiers in Veterinary Science, 2021 - frontiersin.org
Correct placental development during early gestation is considered the main determinant of
fetal growth in late pregnancy. A reduction in maternal nourishment occurring across the …

Inhibition of the CXC motif chemokine 12 (CXCL12) and its receptor CXCR4 reduces utero-placental expression of the VEGF system and increases utero-placental …

RL Ashley, CL Runyan, MM Maestas… - Frontiers in Veterinary …, 2021 - frontiersin.org
The placenta, a unique organ that only develops during pregnancy, is essential for nutrient,
oxygen, and waste exchange between offspring and mother. Yet, despite its importance, the …

Uterine pyruvate metabolic disorder induced by silica nanoparticles act through the pentose phosphate pathway

H Yin, J Li, J Tian, L Ma, J Zhang, Q Zhai, S Yao… - Journal of Hazardous …, 2021 - Elsevier
Silica nanoparticles (SiNPs) have drawn considerable attention due to their environmental
health effects, while enhanced understanding of metabolic disorders has provided insight …