Ten things you should know about transposable elements

G Bourque, KH Burns, M Gehring, V Gorbunova… - Genome biology, 2018 - Springer
Transposable elements (TEs) are major components of eukaryotic genomes. However, the
extent of their impact on genome evolution, function, and disease remain a matter of intense …

Putative origins of cell-free DNA in humans: a review of active and passive nucleic acid release mechanisms

S Grabuschnig, AJ Bronkhorst, S Holdenrieder… - International journal of …, 2020 - mdpi.com
Through various pathways of cell death, degradation, and regulated extrusion, partial or
complete genomes of various origins (eg, host cells, fetal cells, and infiltrating viruses and …

Restricting retrotransposons: a review

JL Goodier - Mobile DNA, 2016 - Springer
Retrotransposons have generated about 40% of the human genome. This review examines
the strategies the cell has evolved to coexist with these genomic “parasites”, focussing on …

The impact of transposable elements in adaptive evolution

L Schrader, J Schmitz - Molecular Ecology, 2019 - Wiley Online Library
The growing knowledge about the influence of transposable elements (TE s) on (a) long‐
term genome and transcriptome evolution;(b) genomic, transcriptomic and epigenetic …

Alu elements: know the SINEs

P Deininger - Genome biology, 2011 - Springer
Alu elements: know the SINEs | Genome Biology Skip to main content SpringerLink Account
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Evolution and diversity of transposable elements in vertebrate genomes

CG Sotero-Caio, RN Platt, A Suh… - Genome biology and …, 2017 - academic.oup.com
Transposable elements (TEs) are selfish genetic elements that mobilize in genomes via
transposition or retrotransposition and often make up large fractions of vertebrate genomes …

[HTML][HTML] Direct competition between hnRNP C and U2AF65 protects the transcriptome from the exonization of Alu elements

K Zarnack, J König, M Tajnik, I Martincorena… - Cell, 2013 - cell.com
There are∼ 650,000 Alu elements in transcribed regions of the human genome. These
elements contain cryptic splice sites, so they are in constant danger of aberrant …

Transposable elements: an abundant and natural source of regulatory sequences for host genes

R Rebollo, MT Romanish, DL Mager - Annual review of genetics, 2012 - annualreviews.org
The fact that transposable elements (TEs) can influence host gene expression was first
recognized more than 50 years ago. However, since that time, TEs have been widely …

Transposons passively and actively contribute to evolution of the two-speed genome of a fungal pathogen

L Faino, MF Seidl, X Shi-Kunne, M Pauper… - Genome …, 2016 - genome.cshlp.org
Genomic plasticity enables adaptation to changing environments, which is especially
relevant for pathogens that engage in “arms races” with their hosts. In many pathogens …

Environmental epigenetics

V Bollati, A Baccarelli - Heredity, 2010 - nature.com
Epigenetics investigates heritable changes in gene expression that occur without changes
in DNA sequence. Several epigenetic mechanisms, including DNA methylation and histone …