Vitamin C in the Treatment of COVID-19

GP Milani, M Macchi, A Guz-Mark - Nutrients, 2021 - mdpi.com
Vitamin C is an essential nutrient that serves as antioxidant and plays a major role as co-
factor and modulator of various pathways of the immune system. Its therapeutic effect during …

The inflammasome in times of COVID-19

JC de Rivero Vaccari, WD Dietrich, RW Keane… - Frontiers in …, 2020 - frontiersin.org
Coronaviruses (CoVs) are members of the genus Betacoronavirus and the Coronaviridiae
family responsible for infections such as severe acute respiratory syndrome (SARS), Middle …

Luteolin activates Tregs to promote IL-10 expression and alleviating caspase-11-dependent pyroptosis in sepsis-induced lung injury

Z Zhang, DY Zhang, K Xie, CJ Wang, F Xu - International …, 2021 - Elsevier
Objectives Acute respiratory distress syndrome (ARDS) is characterized by an excessive
pulmonary inflammatory response. Pyroptosis is a newly form of programmed inflammatory …

[HTML][HTML] Respiratory care for the critical patients with 2019 novel coronavirus

YC Wang, MC Lu, SF Yang, MY Bien, YF Chen… - Respiratory …, 2021 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is transmitted through
respiratory droplets, aerosols and close contact. Cross infections occur because viruses …

The variable nature of vitamin C—does it help when dealing with Coronavirus?

K Grudlewska-Buda, N Wiktorczyk-Kapischke… - Antioxidants, 2022 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is still spreading
worldwide. For this reason, new treatment methods are constantly being researched …

[HTML][HTML] Pulmonary epithelial wound healing and the immune system. Mathematical modeling and bifurcation analysis of a bistable system

CR Lotter, JA Sherratt - Journal of Theoretical Biology, 2025 - Elsevier
Respiratory diseases such as asthma, acute respiratory distress syndrome (ARDS),
influenza or COVID-19 often directly target the epithelium. Elevated immune levels and a …

The role of inflammasomes in COVID-19: potential therapeutic targets

C Sun, H Zhao, Y Han, Y Wang… - Journal of Interferon & …, 2022 - liebertpub.com
The coronavirus 2019 disease (COVID-19) pandemic has caused massive morbidity and
mortality worldwide. In severe cases, it is mainly associated with acute pneumonia, cytokine …

Regulation of cell proliferation and transdifferentiation compensates for ventilator‐induced lung injury mediated by NLRP3 inflammasome activation

H Liu, X Yang, G Liu - Immunity, Inflammation and Disease, 2023 - Wiley Online Library
Background Mechanical ventilation is an important means of respiratory support and
treatment for various diseases. However, its use can lead to serious complications …

A case of secondary tension pneumothorax in COVID-19 pneumonia in a patient with no prior history of lung disease

K Amoah, K Gunasekaran, MS Rahi… - SAGE Open Medical …, 2020 - journals.sagepub.com
Complications that arise in patients with severe COVID-19 pneumonia are acute respiratory
distress syndrome, often leading to mechanical ventilation, shock requiring vasopressors …

Dexamethasone and transdehydroandrosterone significantly reduce pulmonary epithelial cell injuries associated with mechanical ventilation

MKAA Al-Ruweidi, FH Ali, S Shurbaji… - Journal of Applied …, 2021 - journals.physiology.org
Many patients who suffer from pulmonary diseases cannot inflate their lungs normally, as
they need mechanical ventilation (MV) to assist them. The stress associated with MV can …