As nanocarriers (NCs) can improve the solubility of drugs, prevent their degradation by
gastrointestinal (GI) enzymes and promote their transport across the mucus gel layer and …

Oral drug absorption is a process influenced by the physicochemical and biopharmaceutical
properties of the drug and its inter-relationship with the gastrointestinal tract. Drug solubility …

Protein corona significantly affects in vivo fate of nanoparticles including biodistribution and
half-life. Without manipulating the physicochemical properties of nanoparticles with …

In recent years, nanosuspension has been considered effective in the delivery of water-
soluble drugs. One of the main challenges to effective drug delivery is designing an …

Overexpression of IL17RB is associated with poor prognosis and short survival of the breast
cancer patients. IL17RB/IL17B signaling triggers a substantial increase in the cell growth …

Colorectal cancer (CRC) is among the five most commonly diagnosed cancers worldwide,
constituting 6% of all cancers and the third leading cause of cancer death. CRC is the third …

The goal of the current study was to target 7-ethyl-10-hydroxycamptothecin (SN38) orally to
colon tumours by synthesizing a targeting polymer. To achieve the optimum delivery for …

Gene therapy is a novel approach for cancer treatment and investigation for suitable gene
delivery systems is remarkable. Here, preparation of a polyelectrolyte complex containing …

Chitosan has emerged as a promising polysaccharide for gene/siRNA delivery. However,
additional works will be required to modify chitosan nanoparticles. In the present study …

Oral chemotherapy is the most preferred drug administration method due to non-invasive
administration, more convenient, low healthcare cost, and patient compliance in comparison …