Due to the hugely important roles of neurotransmitter acetylcholine (ACh) and amyloid-β
(Aβ) in the pathogenesis of Alzheimer's disease (AD), the development of multi-target …

Alzheimer's disease (AD) is a progressive age‐related neurodegenerative brain disorder,
which leads to loss of memory and other cognitive dysfunction. The underlying mechanisms …

A series of novel quinoline-O-carbamate derivatives was rationally designed for treating
Alzheimer's disease (AD) by multi-target-directed ligands (MTDLs) strategy. The target …

Introduction The brain functional network can describe the spontaneous activity of nerve
cells and reveal the subtle abnormal changes associated with brain disease. It has been …

Based on the multitarget strategy, a series of novel clioquinol− 1-benzyl-1, 2, 3, 6-
tetrahydropyridine hybrids were identified for the potential treatment of Alzheimer's disease …

Alzheimer's disease (AD) is a progressive and neurodegenerative illness which results in
alterations in cognitive development. It is characterized by loss/dysfunction of cholinergic …

PtII based organometallic photosensitizers (PSs) have emerged as novel potent
photodynamic inactivation (PDI) reagents through their enhanced intersystem crossing (ISC) …

With the development trend of an aging society, Alzheimer's disease (AD) has become an
urgent problem in the field of medicine worldwide. Cognitive impairment in AD patients …

Oxidative stress can be a series burden on human health and may lead to many chronic
diseases such as diabetes and neurological disorders. The use of natural products to …

A series of 32 molecules derived from 7-prenyloxy-2, 3-dihydroflavanone and 5‑hydroxy-7-
prenyloxy-2, 3-dihydro-flavanone possessing an inhibitory activity against the …