Cancer stem cells (CSCs) are heterogeneous, possess self-renewal attributes, and
orchestrate important crosstalk in tumors. We propose that the CSC state represents" …

Similarly to our healthy organs, the tumor tissue also constitutes an ecosystem. This implies
that stromal cells acquire an altered phenotype in tandem with tumor cells, thereby …

Tumour-associated macrophages (TAMs) are essential players in the tumour
microenvironment (TME) and modulate various pro-tumorigenic functions such as …

Molecular carcinogenesis is a multistep process that involves acquired abnormalities in key
biological processes. The complexity of cancer pathogenesis is best illustrated in the six …

Growing evidence highlights that glycolysis and tumor-derived lactate could skew tumor-
associated macrophages (TAMs) toward an immunosuppressive phenotype. However, the …

Tumor-associated macrophages (TAMs) are an essential proportion of tumor-infiltrating
immune cells in the tumor microenvironment (TME) and have immunosuppressive functions …

Metabolic reprogramming is akey hallmark of tumors, developed in response to hypoxia and
nutrient deficiency during tumor progression. In both cancer and immune cells, there is a …

Tumor-associated macrophages (TAMs) are significant immunocytes infiltrating the tumor
microenvironment (TME). Recent research has shown that TAMs exhibit diversity in terms of …

Although the impacts of Saccharomyces cerevisiae on cancers are mentioned, data on its
use in mice with cyclic GMP-AMP synthase deficiency (cGAS-/-) are even rarer. Here, 12 …

Gliomas are the most prevailing brain malignancy in both children and adults. Microglia,
which are resident in the central nervous system (CNS), are distributed throughout the brain …