Abstract 'Glomerulonephritis'(GN) is a term used to describe a group of heterogeneous
immune-mediated disorders characterized by inflammation of the filtration units of the kidney …

Podocytes and parietal epithelial cells (PECs) are among the few principal cell types within
the kidney glomerulus, the former serving as a crucial constituent of the kidney filtration …

Background The NLRP3 inflammasome integrates several danger signals into the activation
of innate immunity and inflammation by secreting IL-1β and IL-18. Most published data …

The biology and diversity of glomerular parietal epithelial cells (PECs) are important for
understanding podocyte regeneration and crescent formation. Although protein markers …

Podocytes form the backbone of the glomerular filtration barrier and are exposed to various
mechanical forces throughout the lifetime of an individual. The highly dynamic …

Background FSGS affects the complex three-dimensional morphology of podocytes,
resulting in loss of filtration barrier function and the development of sclerotic lesions …

Since its original description in the 1980s, collapsing glomerulopathy has been the subject
of intense study, and these efforts have uncovered numerous insights into potential disease …

Single cell RNA sequencing (scRNA-seq) is today a common and powerful technology in
biomedical research settings, allowing to profile the whole transcriptome of a very large …

Abstract Aims LncRNA SNHG16 and Toll-like receptor-4 (TLR4) participate in diabetes
nephropathy. This study investigated whether SNHG16 regulates diabetic renal injury (DRI) …

Renal specific outcome trials have become more popular and are increasing the available
armamentarium to diminish the progression of renal decline in patients at greater risk of end …