The schlafen family of proteins and their regulation by interferons

E Mavrommatis, EN Fish… - Journal of Interferon & …, 2013 - liebertpub.com
The Schlafen (SLFN) family of proteins includes several mouse and human members. There
is emerging evidence that members of this family of proteins are involved in important …

To translate, or not to translate: viral and host mRNA regulation by interferon-stimulated genes

MMH Li, MR MacDonald, CM Rice - Trends in cell biology, 2015 - cell.com
Type I interferon (IFN) is one of the first lines of cellular defense against viral pathogens. As
a result of IFN signaling, a wide array of IFN-stimulated gene (ISG) products is upregulated …

Codon-usage-based inhibition of HIV protein synthesis by human schlafen 11

M Li, E Kao, X Gao, H Sandig, K Limmer… - Nature, 2012 - nature.com
In mammals, one of the most pronounced consequences of viral infection is the induction of
type I interferons, cytokines with potent antiviral activity. Schlafen (Slfn) genes are a subset …

Transcriptomic Response of Mussel Gills After a Vibrio splendidus Infection Demonstrates Their Role in the Immune Response

A Saco, M Rey-Campos, B Novoa… - Frontiers in …, 2020 - frontiersin.org
Mussels (Mytilus galloprovincialis) are filter feeder bivalves that are constantly in contact
with a wide range of microorganisms, some of which are potentially pathogenic. How …

Evolution of the Schlafen genes, a gene family associated with embryonic lethality, meiotic drive, immune processes and orthopoxvirus virulence

O Bustos, S Naik, G Ayers, C Casola… - Gene, 2009 - Elsevier
Genes of the Schlafen family, first discovered in mouse, are expressed in hematopoietic
cells and are involved in immune processes. Previous results showed that they are …

The Schlafen family: complex roles in different cell types and virus replication

F Liu, P Zhou, Q Wang, M Zhang… - Cell biology …, 2018 - Wiley Online Library
The Schlafen (slfn) gene family members express broadly, but the research has mainly
focused on human slfn (h‐slfn) and mouse slfn (m‐slfn). The slfn members can be divided …

Synonymous virus genome recoding as a tool to impact viral fitness

MA Martínez, A Jordan-Paiz, S Franco, M Nevot - Trends in microbiology, 2016 - cell.com
Synthetic genome recoding is a novel method of generating viruses with altered
phenotypes, whereby many synonymous mutations are introduced into the protein coding …

Role of interferon α (IFNα)-inducible Schlafen-5 in regulation of anchorage-independent growth and invasion of malignant melanoma cells

E Katsoulidis, E Mavrommatis, J Woodard… - Journal of Biological …, 2010 - ASBMB
IFNα exerts potent inhibitory activities against malignant melanoma cells in vitro and in vivo,
but the mechanisms by which it generates its antitumor effects remain unknown. We …

[HTML][HTML] Expression and regulation of Schlafen (SLFN) family members in primary human monocytes, monocyte-derived dendritic cells and T cells

A Puck, R Aigner, M Modak, P Cejka, D Blaas… - Results in …, 2015 - Elsevier
Schlafen (SLFN/Slfn) family members have been investigated for their involvement in
fundamental cellular processes including growth regulation, differentiation and control of …

Anti-inflammatory activities and mechanisms of Artemisia asiatica ethanol extract

D Jeong, YS Yi, GH Sung, WS Yang, JG Park… - Journal of …, 2014 - Elsevier
Abstract Ethnopharmacological relevance Artemisia asiatica Nakai (Compositae) is a
representative herbal plant used to treat infection and inflammatory diseases. Although …