Clinical application and detection techniques of liquid biopsy in gastric cancer

S Ma, M Zhou, Y Xu, X Gu, M Zou, G Abudushalamu… - Molecular Cancer, 2023 - Springer
Gastric cancer (GC) is one of the most common tumors worldwide and the leading cause of
tumor-related mortality. Endoscopy and serological tumor marker testing are currently the …

Liquid biopsy in gastric cancer: predictive and prognostic biomarkers

Z Zhang, H Wu, W Chong, L Shang, C Jing, L Li - Cell death & disease, 2022 - nature.com
Gastric cancer (GC) is a high-incidence cancer worldwide. Most patients are diagnosed at
an advanced stage, by which time they have limited treatment options and poor prognosis …

Liquid biopsy in cancer current: status, challenges and future prospects

L Ma, H Guo, Y Zhao, Z Liu, C Wang, J Bu… - … and Targeted Therapy, 2024 - nature.com
Cancer has a high mortality rate across the globe, and tissue biopsy remains the gold
standard for tumor diagnosis due to its high level of laboratory standardization, good …

Circulating tumor cells: from new biological insights to clinical practice

X Gu, S Wei, X Lv - Signal Transduction and Targeted Therapy, 2024 - nature.com
The primary reason for high mortality rates among cancer patients is metastasis, where
tumor cells migrate through the bloodstream from the original site to other parts of the body …

[HTML][HTML] Blood-based DNA methylation signatures in cancer: A systematic review

Y Li, Z Fan, Y Meng, S Liu, H Zhan - … Acta (BBA)-Molecular Basis of Disease, 2023 - Elsevier
DNA methylation profiles are in dynamic equilibrium via the initiation of methylation,
maintenance of methylation and demethylation, which control gene expression and …

Clinical applications and perspectives of circulating tumor DNA in gastric cancer

JH Li, DY Zhang, JM Zhu, L Dong - Cancer Cell International, 2024 - Springer
Gastric cancer remains a leading cause of cancer-related death worldwide, largely due to
inadequate screening methods, late diagnosis, and limited treatment options. Liquid biopsy …

Landscape of innovative methods for early diagnosis of gastric cancer: a systematic review

A Orășeanu, MC Brisc, OA Maghiar, H Popa, CM Brisc… - Diagnostics, 2023 - mdpi.com
From a global perspective, gastric cancer (GC) persists as a significant healthcare issue. In
the Western world, the majority of cases are discovered at late stages, when the treatment is …

DNA methylation: an important biomarker and therapeutic target for gastric cancer

Y Zeng, H Rong, J Xu, R Cao, S Li, Y Gao… - Frontiers in …, 2022 - frontiersin.org
Gastric cancer (GC) is a very common malignancy with a poor prognosis, and its occurrence
and development are closely related to epigenetic modifications. Methylation of DNA before …

Clinical applications of circulating tumor DNA profiling in GI cancers

F Battaglin, HJ Lenz - JCO Oncology Practice, 2024 - ascopubs.org
Over the next few years, the analysis of circulating tumor DNA (ctDNA) through liquid biopsy
is expected to enter clinical practice and revolutionize the approach to biomarker testing and …

Extensive methylation analysis of circulating tumor DNA in plasma of patients with gastric cancer

S Nagano, Y Kurokawa, T Hagi, R Yoshioka… - Scientific Reports, 2024 - nature.com
DNA methylation is known to be involved in tumor progression. This is the first study to
perform an extensive methylation analysis of plasma circulating tumor DNA (ctDNA) using …