Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia

B Richter, B Hemmingsen… - Cochrane Database …, 2018 - cochranelibrary.com
Background Intermediate hyperglycaemia (IH) is characterised by one or more
measurements of elevated blood glucose concentrations, such as impaired fasting glucose …

Ectopic fat and insulin resistance: pathophysiology and effect of diet and lifestyle interventions

M Snel, JT Jonker, J Schoones, H Lamb… - International journal …, 2012 - Wiley Online Library
The storage of triglyceride (TG) droplets in nonadipose tissues is called ectopic fat storage.
Ectopic fat is associated with insulin resistance and type 2 diabetes mellitus (T2DM). Not the …

Acne vulgaris: a disease of Western civilization

L Cordain, S Lindeberg, M Hurtado, K Hill… - Archives of …, 2002 - jamanetwork.com
Background In westernized societies, acne vulgaris is a nearly universal skin disease
afflicting 79% to 95% of the adolescent population. In men and women older than 25 years …

Can we apply the National Cholesterol Education Program Adult Treatment Panel definition of the metabolic syndrome to Asians?

CE Tan, S Ma, D Wai, SK Chew, ES Tai - Diabetes care, 2004 - Am Diabetes Assoc
OBJECTIVE—Limited information is available about the metabolic syndrome in Asians.
Furthermore, the definition of central obesity using waist circumference may not be …

The western diet and lifestyle and diseases of civilization

P Carrera-Bastos, M Fontes-Villalba… - Research Reports in …, 2011 - Taylor & Francis
It is increasingly recognized that certain fundamental changes in diet and lifestyle that
occurred after the Neolithic Revolution, and especially after the Industrial Revolution and the …

Cardiovascular disease resulting from a diet and lifestyle at odds with our Paleolithic genome: how to become a 21st-century hunter-gatherer

JH O'Keefe Jr, L Cordain - Mayo Clinic Proceedings, 2004 - Elsevier
Our genetic make-up, shaped through millions of years of evolution, determines our
nutritional and activity needs. Although the human genome has remained primarily …

Genetic and environmental effects on myopia development and progression

E Goldschmidt, N Jacobsen - Eye, 2014 - nature.com
This review aims at elucidating the interaction between genetic and environmental factors in
the aetiology of primarily low myopia. Genetics greatly influence the growth of the eye, but …

[HTML][HTML] Islet amyloid and type 2 diabetes: from molecular misfolding to islet pathophysiology

ETAS Jaikaran, A Clark - Biochimica et Biophysica Acta (BBA)-Molecular …, 2001 - Elsevier
Islet amyloid polypeptide (IAPP, amylin) is secreted from pancreatic islet β-cells and
converted to amyloid deposits in type 2 diabetes. Conversion from soluble monomer, IAPP 1 …

[PDF][PDF] Type 2 diabetes in the young: the evolving epidemic

ZT Bloomgarden - Diabetes care, 2004 - academia.edu
The topic of the International Diabe-tes Federation Consensus conference, held 7–9
February 2003 in Santa Monica, California, was “Type 2 Diabetes in the Young: The …

An evolutionary analysis of the aetiology and pathogenesis of juvenile‐onset myopia

L Cordain, SB Eaton, J Brand Miller… - Acta …, 2002 - Wiley Online Library
The available evidence suggests that both genes and environment play a crucial role in the
development of juvenile‐onset myopia. When the human visual system is examined from an …