Simple Summary Glioblastoma is among the most lethal cancers in humans. Glioblastomas
exhibit a striking heterogeneity, which is maintained by a highly plastic, adaptable …

Evidence has revealed that transcription factors play essential roles in regulation of multiple
cellular processes, including cell proliferation, metastasis, EMT, cancer stem cells and …

Glioblastoma multiforme (GBM) remains incurable despite multimodal treatments after
surgical debulking. Almost all patients with GBM relapse within a narrow margin (2–3 cm) of …

Simple Summary There are few established treatment options for recurrent glioblastoma
(rGBM). Immunotherapy, which potentiates the immune system to counter tumor growth …

Glioma is the most common tumor of the primary central nervous system, and its malignant
phenotype has been shown to be closely related to glioma stem cells (GSCs). Although …

Glioblastoma (GBM) recurrences appear in most cases around the resection cavity borders
and arise from residual GBM cells that cannot be removed by surgery. Here, we propose a …

Purpose Glioma patients, especially recurrent glioma, suffer from a poor prognosis. While
advances to classify glioma on a molecular level improved prognostication at initial …

Surgical resection represents the standard of care for people with newly diagnosed diffuse
gliomas, and the neuropathological and molecular profile of the resected tissue guides …

Background Glioblastoma (GBM), with its high recurrence and mortality rates, makes it the
deadliest neurological malignancy. Oxidative phosphorylation is a highly active cellular …

Glioblastoma is a highly aggressive form of brain cancer characterized by the abundance of
myeloid lineage cells in the tumor microenvironment. Tumor-associated macrophages and …