Structural insights into nuclear transcription by eukaryotic DNA-dependent RNA polymerases
The eukaryotic transcription apparatus synthesizes a staggering diversity of RNA molecules.
The labour of nuclear gene transcription is, therefore, divided among multiple DNA …
The labour of nuclear gene transcription is, therefore, divided among multiple DNA …
Survey and summary transcription by RNA polymerases I and III
MR Paule, RJ White - Nucleic acids research, 2000 - academic.oup.com
The task of transcribing nuclear genes is shared between three RNA polymerases in
eukaryotes: RNA polymerase (pol) I synthesises the large rRNA, pol II synthesises mRNA …
eukaryotes: RNA polymerase (pol) I synthesises the large rRNA, pol II synthesises mRNA …
A novel class of small RNAs: tRNA-derived RNA fragments (tRFs)
New types of small RNAs distinct from microRNAs (miRNAs) are progressively being
discovered in various organisms. In order to discover such novel small RNAs, a library of 17 …
discovered in various organisms. In order to discover such novel small RNAs, a library of 17 …
Transcription termination by nuclear RNA polymerases
P Richard, JL Manley - Genes & development, 2009 - genesdev.cshlp.org
Gene transcription in the cell nucleus is a complex and highly regulated process.
Transcription in eukaryotes requires three distinct RNA polymerases, each of which employs …
Transcription in eukaryotes requires three distinct RNA polymerases, each of which employs …
RNA polymerase backtracking in gene regulation and genome instability
E Nudler - Cell, 2012 - cell.com
RNA polymerase is a ratchet machine that oscillates between productive and backtracked
states at numerous DNA positions. Since its first description 15 years ago, backtracking—the …
states at numerous DNA positions. Since its first description 15 years ago, backtracking—the …
The la protein
SL Wolin, T Cedervall - Annual review of biochemistry, 2002 - annualreviews.org
▪ Abstract Ubiquitous in eukaryotic cells, the La protein associates with the 3′ termini of
many newly synthesized small RNAs. RNAs bound by the La protein include all nascent …
many newly synthesized small RNAs. RNAs bound by the La protein include all nascent …
Purified lupus antigen La recognizes an oligouridylate stretch common to the 3′ termini of RNA polymerase III transcripts
JE Stefano - Cell, 1984 - cell.com
The small ribonucleoproteins recognized by anti-La sera consist mainly of RNA polymerase
Ill products complexed with an antigenic cellular protein of 50 kd. A biochemical procedure …
Ill products complexed with an antigenic cellular protein of 50 kd. A biochemical procedure …
Eukaryotic RNA polymerase
A Sentenac - Critical Reviews in Biochemistry, 1985 - Taylor & Francis
The reading unit for genetic information is a complex enzymatic machinery named “DNA-
dependent RNA polymerase”(EC 2.7. 7.6). In bacteria, a unique enzyme, flanked with a …
dependent RNA polymerase”(EC 2.7. 7.6). In bacteria, a unique enzyme, flanked with a …
Proliferating cell nuclear antigen-dependent abasic site repair in Xenopus laevis oocytes: an alternative pathway of base excision DNA repair
Y Matsumoto, K Kim… - Molecular and cellular …, 1994 - Am Soc Microbiol
DNA damage frequently leads to the production of apurinic/apyrimidinic (AP) sites, which
are presumed to be repaired through the base excision pathway. For detailed analyses of …
are presumed to be repaired through the base excision pathway. For detailed analyses of …
Oligonucleotide sequence signaling transcriptional termination of vaccinia virus early genes.
L Yuen, B Moss - Proceedings of the National Academy of …, 1987 - National Acad Sciences
In an in vitro system containing enzymes extracted from vaccinia virions, transcription of the
vaccinia growth factor gene terminated approximately 50 base pairs downstream of a …
vaccinia growth factor gene terminated approximately 50 base pairs downstream of a …