Molecular science entails the study of structures and properties of materials at the level of
single molecules or small interacting complexes of molecules. Moving beyond single …

Conventional π-conjugated luminophores suffer from problems such as emission
quenching, biotoxicity, environmental pollution, etc. The emerging nonconjugated and …

Hybrid small-molecule/protein fluorescent probes are powerful tools for visualizing protein
localization and function in living cells. These hybrid probes are constructed by diverse site …

Amyloids are a broad class of proteins and peptides that can misfold and assemble into long
unbranched fibrils with a cross-β conformation. These misfolding and aggregation events …

Density functional theory (DFT) is the most widely-used electronic structure approximation
across chemistry, physics, and materials science. Every year, thousands of papers report …

Microenvironment-related parameters like viscosity, polarity, and pH play important roles in
controlling the physical or chemical behaviors of local molecules, which determine the …

Molecular rotor‐based fluorophores (RBFs) have been widely used in many fields. However,
the lack of control of their viscosity sensitivity limits their application. Herein, this problem is …

Protein misfolding and aggregation, a key contributor to the progression of numerous
neurodegenerative diseases, results in functional deficiencies and the creation of harmful …

Parkinson's disease (PD), as the second most common neurodegenerative disease, is
caused by complex pathological processes and currently remains very difficult to treat. PD …

In vivo fluorescent monitoring of physiological processes with high‐fidelity is essential in
disease diagnosis and biological research, but faces extreme challenges due to …