Invasive fungal infections pose an important threat to public health and are an under-
recognized component of antimicrobial resistance, an emerging crisis worldwide. Across a …

Prior to the SARS-CoV-2 pandemic, antibiotic resistance was listed as the major global
health care priority. Some analyses, including the O'Neill report, have predicted that deaths …

Human fungal infections are a historically neglected area of disease research, yet they
cause more than 1.5 million deaths every year. Our understanding of the pathophysiology of …

The number of antifungal classes is small, and resistance is becoming a much more
frequent problem. Much greater emphasis needs to be placed on susceptibility testing and …

Candida albicans is a multimorphic commensal organism and opportunistic fungal pathogen
in humans. A morphological switch between unicellular budding yeast and multicellular …

The COVID-19 pandemic has highlighted the detrimental effect of secondary pathogens in
patients with a primary viral insult. In addition to superinfections with bacterial pathogens …

Since its first description in 2009, Candida auris has, so far, resulted in large hospital
outbreaks worldwide and is considered an emerging global public health threat …

Antifungal stewardship (AFS) programs are key to optimizing antifungal use and improving
outcomes in patients with invasive fungal infections. Our systematic literature review …

Antimicrobial stewardship refers to a well-coordinated program which promotes the scientific
and rational use of antimicrobials, reduces the chances of drug resistance and improves …

Invasive fungal diseases (IFD) are serious infections associated with high mortality,
particularly in immunocompromised patients. The prescribing of antifungal agents to prevent …