Linking prenatal environmental exposures to lifetime health with epigenome-wide association studies: state-of-the-science review and future recommendations

KM Bakulski, F Blostein, SJ London - Environmental health …, 2023 - ehp.niehs.nih.gov
Background: The prenatal environment influences lifetime health; epigenetic mechanisms
likely predominate. In 2016, the first international consortium paper on cigarette smoking …

[HTML][HTML] Effective and economical cell therapy for hair regeneration

JH Sung - Biomedicine & Pharmacotherapy, 2023 - Elsevier
We reviewed and summarized the latest reports on the characteristics of stem cells and
follicular cells that are under development for hair loss treatment. Compared with …

Stimulation by exosomes from hypoxia-preconditioned hair follicle mesenchymal stem cells facilitates mitophagy by inhibiting the PI3K/AKT/mTOR signaling pathway …

N Li, L Zhao, X Geng, J Liu, X Zhang, Y Hu, J Qi… - …, 2024 - pmc.ncbi.nlm.nih.gov
Background: Ulcerative colitis (UC) is an intestinal inflammatory disease that is strongly
associated with mitochondrial damage and dysfunction as well as mitophagy and lacks of …

Assessing Biomaterial‐Induced Stem Cell Lineage Fate by Machine Learning‐Based Artificial Intelligence

Y Zhou, X Ping, Y Guo, BC Heng, Y Wang… - Advanced …, 2023 - Wiley Online Library
Current functional assessment of biomaterial‐induced stem cell lineage fate in vitro mainly
relies on biomarker‐dependent methods with limited accuracy and efficiency. Here a …

PBX1 attenuates hair follicle-derived mesenchymal stem cell senescence and apoptosis by alleviating reactive oxygen species-mediated DNA damage instead of …

Y Wang, Y Sui, A Lian, X Han, F Liu, K Zuo… - Frontiers in cell and …, 2021 - frontiersin.org
Tissues and organs undergo structural deterioration and functional decline during aging.
DNA damage is considered a major cause of stem cell senescence. Although stem cells …

Human hair follicle-derived mesenchymal stromal cells from the lower dermal sheath as a competitive alternative for immunomodulation

B Hernaez-Estrada, A Gonzalez-Pujana, A Cuevas… - Biomedicines, 2022 - mdpi.com
Mesenchymal stromal cells (MSCs) have unique immunomodulatory capacities. We
investigated hair follicle-derived MSCs (HF-MSCs) from the dermal sheath, which are …

PBX1-SIRT1 positive feedback loop attenuates ROS-mediated HF-MSC senescence and apoptosis

Y Wang, Y Sui, Y Niu, D Liu, Q Xu, F Liu, K Zuo… - Stem cell reviews and …, 2023 - Springer
Stem cell senescence and depletion are major causes of aging and aging-related diseases.
The NAD (Nicotinamide adenine dinucleotide)–SIRT1 (Silent Information Regulator 1) …

The role of mesenchymal stem cells in hair regeneration and hair cycle

C Ma, M Cheng, Y Wu, X Xu - Stem Cells and Development, 2024 - liebertpub.com
The health of hair is directly related to people's health and appearance. Hair has key
physiological functions, including skin protection and temperature regulation. Hair follicle …

Mesenchymal stem cells from mouse hair follicles reduce hypertrophic scarring in a murine wound healing model

H Li, M Ziemer, I Stojanovic, T Saksida… - Stem Cell Reviews and …, 2022 - Springer
Wound healing of acute full-thickness injuries and chronic non-healing ulcers leads to
delayed wound closure, prolonged recovery period and hypertrophic scarring, generating a …

Mesenchymal Stem Cells Isolated from Equine Hair Follicles Using a Method of Air-Liquid Interface

H Li, S Xiong, FF Masieri, S Monika, B Lethaus… - Stem Cell Reviews and …, 2023 - Springer
Equine mesenchymal stem cells (MSC) of various origins have been identified in horses,
including MSCs from the bone marrow and adipose tissue. However, these stem cell …