Computational methods for in situ structural studies with cryogenic electron tomography

C Zhao, D Lu, Q Zhao, C Ren, H Zhang… - Frontiers in Cellular …, 2023 - frontiersin.org
Cryo-electron tomography (cryo-ET) plays a critical role in imaging microorganisms in situ in
terms of further analyzing the working mechanisms of viruses and drug exploitation, among …

[HTML][HTML] A Bayesian framework for cryo-EM heterogeneity analysis using regularized covariance estimation

MA Gilles, A Singer - bioRxiv, 2023 - ncbi.nlm.nih.gov
Proteins and the complexes they form are central to nearly all cellular processes. Their
flexibility, expressed through a continuum of states, provides a window into their biological …

Fast principal component analysis for cryo-electron microscopy images

NF Marshall, O Mickelin, Y Shi, A Singer - Biological imaging, 2023 - cambridge.org
Principal component analysis (PCA) plays an important role in the analysis of cryo-electron
microscopy (cryo-EM) images for various tasks such as classification, denoising …

Subspace method of moments for ab initio 3-D single-particle Cryo-EM reconstruction

J Hoskins, Y Khoo, O Mickelin, A Singer… - arXiv preprint arXiv …, 2024 - arxiv.org
Cryo-electron microscopy (Cryo-EM) is a widely-used technique for recovering the 3-D
structure of biological molecules from a large number of experimentally generated noisy 2-D …

Computational methods for three-dimensional electron microscopy (3DEM)

JJ Fernández, A Martínez-Sánchez - Computer Methods and …, 2022 - digital.csic.es
Revolutionary technical and computational advancements in the last decade have
established three-dimensional electron microscopy (3DEM) as an essential structural tool for …

Fast principal component analysis for cryo-EM images

NF Marshall, O Mickelin, Y Shi, A Singer - arXiv preprint arXiv:2210.17501, 2022 - arxiv.org
Principal component analysis (PCA) plays an important role in the analysis of cryo-EM
images for various tasks such as classification, denoising, compression, and ab-initio …

Filtering Methods for Biomedical Image Denoising

T Zhao - 2023 - preprints.org
In this paper, the filtering method of biomedical image denoising is described
comprehensively. Firstly, it introduces the biomedical image denoising, describes the …