Pertussis toxin suppresses dendritic cell-mediated delivery of B. pertussis into lung-draining lymph nodes
N Klimova, J Holubova, G Streparola, J Tomala… - PLoS …, 2022 - journals.plos.org
The adenylate cyclase (ACT) and the pertussis (PT) toxins of Bordetella pertussis exert
potent immunomodulatory activities that synergize to suppress host defense in the course of …
potent immunomodulatory activities that synergize to suppress host defense in the course of …
Melanin Produced by Bordetella parapertussis Confers a Survival Advantage to the Bacterium during Host Infection
Y Hiramatsu, T Nishida, DK Nugraha, F Sugihara… - Msphere, 2021 - Am Soc Microbiol
Bordetella parapertussis causes respiratory infection in humans, with a mild pertussis
(whooping cough)-like disease. The organism produces a brown pigment, the nature and …
(whooping cough)-like disease. The organism produces a brown pigment, the nature and …
Adenylate cyclase toxin of Bordetella parapertussis disrupts the epithelial barrier granting the bacterial access to the intracellular space of epithelial cells
JP Gorgojo, MC Carrica, CM Baroli, HA Valdez… - Plos one, 2023 - journals.plos.org
B. parapertussis is one of the etiological agents of whooping cough. Once inhaled, the
bacteria bind to the respiratory epithelium and start the infection. Little is known about this …
bacteria bind to the respiratory epithelium and start the infection. Little is known about this …
Bordetella parapertussis adenylate cyclase toxin promotes the bacterial survival to the encounter with macrophages
M del Carmen Carrica, JP Gorgojo, YA Lamberti… - Microbial …, 2023 - Elsevier
B. parapertussis is a whooping cough etiological agent, whose incidence in the population
has increased remarkably. Virulence factors involved in the bacterial infection, however …
has increased remarkably. Virulence factors involved in the bacterial infection, however …
Different roles of conserved tyrosine residues of the acylated domains in folding and activity of RTX toxins
A Lepesheva, A Osickova, J Holubova, D Jurnecka… - Scientific Reports, 2021 - nature.com
Pore-forming repeats in toxins (RTX) are key virulence factors of many Gram-negative
pathogens. We have recently shown that the aromatic side chain of the conserved tyrosine …
pathogens. We have recently shown that the aromatic side chain of the conserved tyrosine …
Identificació i caracterització de proteïnes i estructures de superfície de Bordetella pertussis com a potencials nous candidats vacunals
A Mir Cros - 2021 - openaccess.uoc.edu
Entre les possibles causes implicades en el ressorgiment de la tosferina al llarg dels darrers
anys, destaca l'adaptació de Bordetella pertussis a la immunitat conferida per les vacunes …
anys, destaca l'adaptació de Bordetella pertussis a la immunitat conferida per les vacunes …