Precision medicine advances in idiopathic pulmonary fibrosis

T Karampitsakos, BM Juan-Guardela, A Tzouvelekis… - …, 2023 - thelancet.com
Idiopathic pulmonary fibrosis (IPF) is a highly heterogeneous, unpredictable and ultimately
lethal chronic lung disease. Over the last decade, two anti-fibrotic agents have been shown …

Mechanisms of organ fibrosis: Emerging concepts and implications for novel treatment strategies

I Lurje, NT Gaisa, R Weiskirchen, F Tacke - Molecular Aspects of Medicine, 2023 - Elsevier
Fibrosis, or tissue scarring, develops as a pathological deviation from the physiological
wound healing response and can occur in various organs such as the heart, lung, liver …

Pulmonary fibrosis: from pathogenesis to clinical decision-making

T Koudstaal, M Funke-Chambour, M Kreuter… - Trends in molecular …, 2023 - cell.com
Pulmonary fibrosis (PF) encompasses a spectrum of chronic lung diseases that
progressively impact the interstitium, resulting in compromised gas exchange …

Molecular mechanisms and cellular contribution from lung fibrosis to lung cancer development

AV Samarelli, V Masciale, B Aramini, GP Coló… - International journal of …, 2021 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, fibrosing interstitial lung
disease (ILD) of unknown aetiology, with a median survival of 2–4 years from the time of …

Progress in understanding and treating idiopathic pulmonary fibrosis: Recent insights and emerging therapies

H Guo, J Sun, S Zhang, Y Nie, S Zhou… - Frontiers in …, 2023 - frontiersin.org
Idiopathic pulmonary fibrosis (IPF) is a long-lasting, continuously advancing, and irrevocable
interstitial lung disorder with an obscure origin and inadequately comprehended …

Identifying potential biomarkers of idiopathic pulmonary fibrosis through machine learning analysis

Z Wu, H Chen, S Ke, L Mo, M Qiu, G Zhu, W Zhu… - Scientific Reports, 2023 - nature.com
Idiopathic pulmonary fibrosis (IPF) is the most common and serious type of idiopathic
interstitial pneumonia, characterized by chronic, progressive, and low survival rates, while …

[HTML][HTML] Raman microspectroscopy identifies fibrotic tissues in collagen-related disorders via deconvoluted collagen type I spectra

L Becker, CE Lu, IA Montes-Mojarro, SL Layland… - Acta Biomaterialia, 2023 - Elsevier
Fibrosis is a consequence of the pathological remodeling of extracellular matrix (ECM)
structures in the connective tissue of an organ. It is often caused by chronic inflammation …

Idiopathic pulmonary fibrosis

F León-Román, C Valenzuela… - Medicina Clínica (English …, 2022 - Elsevier
Idiopathic pulmonary fibrosis is defined as a chronic progressive fibrosing interstitial
pneumonia of unknown etiology. There are intrinsic and extrinsic risk factors that could favor …

Molecular and genetic biomarkers in idiopathic pulmonary fibrosis: where are we now?

I Tomos, I Roussis, AM Matthaiou, K Dimakou - Biomedicines, 2023 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) represents a chronic progressive fibrotic interstitial lung
disease of unknown cause with an ominous prognosis. It remains an unprecedent clinical …

Baseline serum Krebs von den Lungen-6 as a biomarker for the disease progression in idiopathic pulmonary fibrosis

C Chung, J Kim, HS Cho, HC Kim - Scientific Reports, 2022 - nature.com
Disease progression (DP) is an important parameter for the prognosis of idiopathic
pulmonary fibrosis (IPF). This study aimed to evaluate the baseline serum biomarkers for …