Recently, mitochondria have been identified as important contributors to the virulence and
drug tolerance of human fungal pathogens. In different scenarios, either hypo-or …

In recent years, the role of mitochondria in pathogenic fungi in terms of azole resistance and
fungal pathogenicity has been a rapidly developing field. In this review, we describe the …

To colonise their host, pathogens must counter local environmental and immunological
challenges. Here, we reveal that the fungal pathogen Candida albicans exploits diverse host …

Candida albicans causes superficial to systemic infections in immuno-compromised
individuals. The concomitant use of fungistatic drugs and the lack of cidal drugs frequently …

Organisms must adapt to changes in oxygen tension if they are to exploit the energetic
benefits of reducing oxygen while minimizing the potentially damaging effects of oxidation …

Amino acids are among the earliest identified inducers of yeast-to-hyphal transitions in
Candida albicans, an opportunistic fungal pathogen of humans. Here, we show that the …

Neutrophils are found within Candida albicans biofilms in vivo and could play a crucial role
in clearing the pathogen from biofilms forming on catheters and mucosal surfaces. Our goal …

For the human fungal pathogen Candida albicans, metabolic flexibility and the ability to
transition between yeast and filamentous growth states are key virulence traits that enable …

Cryptococcus gattii is an emerging intracellular pathogen and the cause of the largest
primary outbreak of a life-threatening fungal disease in a healthy population. Outbreak …

Among the several mechanisms of multidrug resistance (MDR), overexpression of drug
efflux pumps CaCdr1p and CaMdr1p belonging to ATP binding cassette (ABC) and major …