Cancer is a heavy burden for humans across the world with high morbidity and mortality.
Transcription factors including sex determining region Y (SRY)-related high-mobility group …

Glioblastoma (GBM) is highly invasive and the deadliest brain tumor in adults. It is
characterized by inter-tumor and intra-tumor heterogeneity, short patient survival, and lack of …

Rationale: Accumulating evidence demonstrated that long noncoding RNAs (lncRNAs)
involved in the regulation of the immune system and displayed a cell-type-specific pattern in …

Abstract The Cancer Genome Atlas (TCGA) has used the latest sequencing and analysis
methods to identify somatic variants across thousands of tumours. Here we present data and …

The chemical modification of RNA is a newly discovered epigenetic regulation mechanism
in cells and plays a crucial role in a variety of biological processes. N6-methyladenine (m6A) …

Both genome-wide genetic and epigenetic alterations are fundamentally important for the
development of cancers, but the interdependence of these aberrations is poorly understood …

Background Gliomas are one of the most common types of primary tumors in central nervous
system. Previous studies have found that macrophages actively participate in tumor growth …

Glioblastoma (GB) is the most frequent and aggressive primary tumor of the central nervous
system. Prognosis remains poor despite ongoing progress. In cases where the gadolinium …

Glioblastoma is the most common and most aggressive primary brain tumor. Despite
maximum treatment, patients only have a median survival time of 15 months, because of the …

The methylation status of the O 6-methylguanine-DNA methyltransferase (MGMT) gene is an
important predictive biomarker for benefit from alkylating agent therapy in glioblastoma …