Autonomic control of cerebral blood flow: fundamental comparisons between peripheral and cerebrovascular circulations in humans

JL Koep, CE Taylor, JS Coombes… - The Journal of …, 2022 - Wiley Online Library
Understanding the contribution of the autonomic nervous system to cerebral blood flow
(CBF) control is challenging, and interpretations are unclear. The identification of calcium …

Application of positron emission tomography in psychiatry—methodological developments and future directions

S Cervenka, A Frick, R Bodén, M Lubberink - Translational Psychiatry, 2022 - nature.com
Mental disorders represent an increasing source of disability and high costs for societies
globally. Molecular imaging techniques such as positron emission tomography (PET) …

Neurotransmitter receptor densities are associated with changes in regional Cerebral blood flow during clinical ongoing pain

A Vamvakas, T Lawn, M Veronese… - Human Brain …, 2022 - Wiley Online Library
Arterial spin labelling (ASL) plays an increasingly important role in neuroimaging pain
research but does not provide molecular insights regarding how regional cerebral blood …

Neuroimaging with PET/MR: moving beyond 3 T in preclinical systems, when for clinical practice?

AS Perera Molligoda Arachchige - Clinical and Translational Imaging, 2023 - Springer
With the advent of ultra-high-field (UHF) imaging and integrated PET/MRI systems at the
beginning of the twentyfirst century, it seems that the field of neurological disease research …

PET as a translational tool in drug development for neuroscience compounds

A Varrone, C Bundgaard… - Clinical Pharmacology …, 2022 - Wiley Online Library
In central nervous system drug discovery programs, early development of new chemical
entities (NCEs) requires a multidisciplinary strategy and a translational approach to obtain …

Methods for quantifying neurotransmitter dynamics in the living brain with PET imaging

J Ceccarini, H Liu, K Van Laere, ED Morris… - Frontiers in …, 2020 - frontiersin.org
Positron emission tomography (PET) neuroimaging in neuropsychiatry is a powerful tool for
the quantification of molecular brain targets to characterize disease, assess disease subtype …

Partial volume correction of PET image data using geometric transfer matrices based on uniform B-splines

JB Mandeville, N Efthimiou… - Physics in Medicine …, 2024 - iopscience.iop.org
Objective. Most methods for partial volume correction (PVC) of positron emission
tomography (PET) data employ anatomical segmentation of images into regions of interest …

Challenges and perspectives of the hybridization of PET with functional MRI or ultrasound for neuroimaging

N Tournier, C Comtat, V Lebon, JL Gennisson - Neuroscience, 2021 - Elsevier
Hybridization of positron emission tomography (PET) with other functional neuroimaging
techniques such as functional magnetic resonance imaging (fMRI) or functional ultrasound …

Breaking Barriers: Exploring Neurotransmitters through In Vivo vs. In Vitro Rivalry

GP Lachance, D Gauvreau, É Boisselier… - Sensors, 2024 - mdpi.com
Neurotransmitter analysis plays a pivotal role in diagnosing and managing
neurodegenerative diseases, often characterized by disturbances in neurotransmitter …

mGluR5 and GABAA receptor‐specific parametric PET atlas construction—PET/MR data processing pipeline, validation, and application

N Kaulen, R Rajkumar, C Régio Brambilla… - Human brain …, 2022 - Wiley Online Library
The glutamate and γ‐aminobutyric acid neuroreceptor subtypes mGluR5 and GABAA are
hypothesized to be involved in the development of a variety of psychiatric diseases …