Designing improved active peptides for therapeutic approaches against infectious diseases

B Gomes, MT Augusto, MR Felício, A Hollmann… - Biotechnology …, 2018 - Elsevier
Infectious diseases are one of the main causes of human morbidity and mortality. In the last
few decades, pathogenic microorganisms' resistance to conventional drugs has been …

Antimicrobial peptides in 2014

G Wang, B Mishra, K Lau, T Lushnikova, R Golla… - Pharmaceuticals, 2015 - mdpi.com
This article highlights new members, novel mechanisms of action, new functions, and
interesting applications of antimicrobial peptides reported in 2014. As of December 2014 …

Snake venom peptides: Tools of biodiscovery

A Munawar, SA Ali, A Akrem, C Betzel - Toxins, 2018 - mdpi.com
Nature endowed snakes with a lethal secretion known as venom, which has been fine-tuned
over millions of years of evolution. Snakes utilize venom to subdue their prey and to survive …

Mechanisms of bacterial membrane permeabilization by crotalicidin (Ctn) and its fragment Ctn (15–34), antimicrobial peptides from rattlesnake venom

C Pérez-Peinado, SA Dias, MM Domingues… - Journal of Biological …, 2018 - ASBMB
Crotalicidin (Ctn), a cathelicidin-related peptide from the venom of a South American
rattlesnake, possesses potent antimicrobial, antitumor, and antifungal properties. Previously …

Identification and characterization of the first cathelicidin from sea snakes with potent antimicrobial and anti-inflammatory activity and special mechanism

L Wei, J Gao, S Zhang, S Wu, Z Xie, G Ling… - Journal of Biological …, 2015 - ASBMB
Cathelicidins are a family of gene-encoded peptide effectors of innate immunity found
exclusively in vertebrates. They play pivotal roles in host immune defense against microbial …

Minor snake venom proteins: Structure, function and potential applications

J Boldrini-França, CT Cologna, MB Pucca… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Snake venoms present a great diversity of pharmacologically active compounds that may be
applied as research and biotechnological tools, as well as in drug development and …

Antibiofilm Activity on Candida albicans and Mechanism of Action on Biomembrane Models of the Antimicrobial Peptide Ctn[15–34]

FLL Aguiar, NC Santos… - International journal of …, 2020 - mdpi.com
Ctn [15–34], the C-terminal fragment of crotalicidin, an antimicrobial peptide from the South
American rattlesnake Crotalus durissus terrificus venom, displays remarkable anti-infective …

Cell-penetrating peptides derived from animal venoms and toxins

G Rádis-Baptista - Toxins, 2021 - mdpi.com
Cell-penetrating peptides (CPPs) comprise a class of short polypeptides that possess the
ability to selectively interact with the cytoplasmic membrane of certain cell types, translocate …

Snake venom cathelicidins as natural antimicrobial peptides

EN De Barros, RM Gonçalves, MH Cardoso… - Frontiers in …, 2019 - frontiersin.org
Bioactive small molecules isolated from animals, plants, fungi and bacteria, including natural
antimicrobial peptides, have shown great therapeutic potential worldwide. Among these …

Biologically active peptides from venoms: applications in antibiotic resistance, cancer, and beyond

L Ageitos, MDT Torres… - International Journal of …, 2022 - mdpi.com
Peptides are potential therapeutic alternatives against global diseases, such as
antimicrobial-resistant infections and cancer. Venoms are a rich source of bioactive peptides …