The calcium/calmodulin-dependent kinases II and IV as therapeutic targets in neurodegenerative and neuropsychiatric disorders

K Sałaciak, A Koszałka, E Żmudzka… - International Journal of …, 2021 - mdpi.com
CaMKII and CaMKIV are calcium/calmodulin-dependent kinases playing a rudimentary role
in many regulatory processes in the organism. These kinases attract increasing interest due …

Calcium/calmodulin-dependent protein kinase IV: A multifunctional enzyme and potential therapeutic target

H Naz, A Islam, F Ahmad, MI Hassan - Progress in biophysics and …, 2016 - Elsevier
The calcium/calmodulin-dependent protein kinase IV (CAMKIV) belongs to the
serine/threonine protein kinase family, and is primarily involved in transcriptional regulation …

Making immotile sperm motile using high-frequency ultrasound

A Vafaie, MR Raveshi, C Devendran, R Nosrati… - Science …, 2024 - science.org
Sperm motility is a natural selection with a crucial role in both natural and assisted
reproduction. Common methods for increasing sperm motility are by using chemicals that …

CatSper channels are regulated by protein kinase A

G Orta, JL De La Vega-Beltran, D Martín-Hidalgo… - Journal of Biological …, 2018 - ASBMB
Mammalian sperm must undergo capacitation as a preparation for entering into
hyperactivated motility, undergoing the acrosome reaction, and acquiring fertilizing ability …

High throughput small RNA and transcriptome sequencing reveal capacitation-related microRNAs and mRNA in boar sperm

Y Li, RH Li, MX Ran, Y Zhang, K Liang, YN Ren… - Bmc Genomics, 2018 - Springer
Background Capacitation, a prerequisite for oocyte fertilization, is a complex process
involving series of structural and functional changes in sperms such as membrane …

Introduction to the pathways involved in the activation and regulation of sperm motility: A review of the relevance of ion channels

DK Swain, P Sharma, N Shah, M Sethi… - Animal reproduction …, 2022 - Elsevier
To participate in sperm–oocyte fusion, spermatozoa need to be motile. In the testes,
spermatozoa are immotile, although these gametes acquire the capacity for motility during …

Understanding sperm motility mechanisms and the implication of sperm surface molecules in promoting motility

S Chakraborty, S Saha - Middle East Fertility Society Journal, 2022 - Springer
Background It is estimated that approximately 8–12% of couples globally face problems
associated with infertility. A large number of men exhibit suboptimal sperm parameters …

Calcium regulates motility and protein phosphorylation by changing cAMP and ATP concentrations in boar sperm in vitro

X Li, L Wang, Y Li, N Zhao, L Zhen, J Fu… - Animal reproduction …, 2016 - Elsevier
Considering the importance of calcium (Ca 2+) in regulating sperm capacitation,
hyperactivation and acrosome reaction, little is known about the molecular mechanism of …

Trace and essential elements as vital components to improve the performance of the male reproductive system: implications in cell signaling pathways

A Morabbi, M Karimian - Journal of Trace Elements in Medicine and …, 2024 - Elsevier
Successful male fertilization requires the main processes such as normal spermatogenesis,
sperm capacitation, hyperactivation, and acrosome reaction. The progress of these …

The ideal holding time for boar semen is 24 h at 17 C prior to short-cryopreservation protocols

MA Torres, MS Monteiro, MS Passarelli, FO Papa… - Cryobiology, 2019 - Elsevier
Boar semen cannot be immediately cryopreserved, it need be hold at 17° C prior to
cryopreservation, holding time has been used to improve cryopreserved boar semen, since …