Ligamentum flavum fibrosis and hypertrophy: molecular pathways, cellular mechanisms, and future directions

C Sun, H Zhang, X Wang, X Liu - The FASEB Journal, 2020 - Wiley Online Library
Hypertrophy of ligamentum flavum (LF), along with disk protrusion and facet joints
degeneration, is associated with the development of lumbar spinal canal stenosis (LSCS) …

The MIST guidelines: the lumbar spinal stenosis consensus group guidelines for minimally invasive spine treatment

TR Deer, JS Grider, JE Pope, S Falowski… - Pain …, 2019 - Wiley Online Library
Background Lumbar spinal stenosis (LSS) can lead to compression of neural elements and
manifest as low back and leg pain. LSS has traditionally been treated with a variety of …

Factors associated with the thickness of the ligamentum flavum: is ligamentum flavum thickening due to hypertrophy or buckling?

N Altinkaya, T Yildirim, S Demir, O Alkan, FB Sarica - Spine, 2011 - journals.lww.com
Study Design. Ligamentum flavum (LF) thickness was measured by using lumbar magnetic
resonance imaging in patients with low back or leg pain. Objective. This study investigated …

[HTML][HTML] Analysis of the relationship between ligamentum flavum thickening and lumbar segmental instability, disc degeneration, and facet joint osteoarthritis in lumbar …

T Yoshiiwa, M Miyazaki, N Notani, T Ishihara… - Asian spine …, 2016 - ncbi.nlm.nih.gov
Analysis of the Relationship between Ligamentum Flavum Thickening and Lumbar
Segmental Instability, Disc Degeneration, and Facet Joint Osteoarthritis in Lumbar Spinal …

Minimally invasive lumbar decompression: a review of indications, techniques, efficacy and safety

S Jain, T Deer, D Sayed, P Chopra, S Wahezi… - Pain …, 2020 - Taylor & Francis
Lumbar spinal stenosis is a common degenerative spine condition. In properly selected
patients, minimally invasive lumbar decompression (mild®) may be an option to improve …

Lumbar spinal stenosis: therapeutic options review

S Costandi, B Chopko, M Mekhail, T Dews… - Pain …, 2015 - Wiley Online Library
Lumbar spinal stenosis (LSS) functionally impacts significant numbers of Americans per
year. Current estimates place the number of Americans suffering from senescent lumbar …

Chondrogenic and fibrotic process in the ligamentum flavum of patients with lumbar spinal canal stenosis

Y Yabe, Y Hagiwara, A Ando, M Tsuchiya, T Minowa… - Spine, 2015 - journals.lww.com
Study Design. A histological, biological, and immunohisto-chemical study of human lumbar
ligamentum flavum. Objective. To analyze changes in the hypertrophied ligamentum flavum …

Harpagophytum procumbens Inhibits Iron Overload‐Induced Oxidative Stress through Activation of Nrf2 Signaling in a Rat Model of Lumbar Spinal Stenosis

JY Hong, H Kim, J Lee, WJ Jeon… - … Medicine and Cellular …, 2022 - Wiley Online Library
Lumbar spinal stenosis (LSS) is a common degenerative spinal condition in older
individuals that causes impaired walking and other disabilities due to severe lower back and …

Long‐Term Results of Percutaneous Lumbar Decompression mild® for Spinal Stenosis

N Mekhail, R Vallejo, MH Coleman… - Pain …, 2012 - Wiley Online Library
Background: Lumbar spinal stenosis (LSS) generally occurs from a combination of
degenerative changes occurring in the lumbar spine. These include hypertrophy of …

[HTML][HTML] Thickness of the ligamentum flavum: correlation with age and its asymmetry-an magnetic resonance imaging study

VS Kolte, S Khambatta, MV Ambiye - Asian spine journal, 2015 - ncbi.nlm.nih.gov
Purpose This study is an attempt to measure and compare the thickening of the LF on both
the sides with the use of magnetic resonance imaging, to investigate if there is a …