M Kremer, LJ Becker, M Barrot… - European Journal of …, 2021 - Wiley Online Library
Mood disorders such as depression and anxiety are frequently observed in patients suffering from chronic pain. Over time, different tests and models have been developed in …
Advancing perovskite solar cell technologies toward their theoretical power conversion efficiency (PCE) requires delicate control over the carrier dynamics throughout the entire …
While depression and chronic pain are frequently comorbid, underlying neuronal circuits and their psychopathological relevance remain poorly defined. Here we show in mice that …
TD Wilson, S Valdivia, A Khan, HS Ahn, AP Adke… - Cell reports, 2019 - cell.com
Pain perception is essential for survival and can be amplified or suppressed by expectations, experiences, and context. The neural mechanisms underlying bidirectional …
F Barthas, J Sellmeijer, S Hugel, E Waltisperger… - Biological …, 2015 - Elsevier
Background Besides chronic stress, chronic pain is a prevalent determinant for depression. Changes induced in specific brain regions by sustained pain may alter the processing of …
The amygdala is a structure of the temporal lobe thought to be involved in assigning emotional significance to environmental information and triggering adapted physiological …
J Sellmeijer, V Mathis, S Hugel, XH Li… - Journal of …, 2018 - Soc Neuroscience
Pain associates both sensory and emotional aversive components, and often leads to anxiety and depression when it becomes chronic. Here, we characterized, in a mouse …
Pain and depression are frequently comorbid disorders, but the mechanism underlying this association is unknown. Here, we report that brain indoleamine 2, 3-dioxygenase 1 (IDO1) …
N Yamauchi, K Sato, K Sato, S Murakawa… - Science …, 2022 - science.org
The comorbidity of chronic pain and mental dysfunctions such as depression and anxiety disorders has long been recognized, but the underlying mechanisms remain poorly …