Tests and models of nociception and pain in rodents

M Barrot - Neuroscience, 2012 - Elsevier
Nociception and pain is a large field of both neuroscience and medical research. Over time,
various tests and models were developed in rodents to provide tools for fundamental and …

How to study anxiety and depression in rodent models of chronic pain?

M Kremer, LJ Becker, M Barrot… - European Journal of …, 2021 - Wiley Online Library
Mood disorders such as depression and anxiety are frequently observed in patients
suffering from chronic pain. Over time, different tests and models have been developed in …

Interface engineering of highly efficient perovskite solar cells

H Zhou, Q Chen, G Li, S Luo, T Song, HS Duan… - Science, 2014 - science.org
Advancing perovskite solar cell technologies toward their theoretical power conversion
efficiency (PCE) requires delicate control over the carrier dynamics throughout the entire …

The basolateral amygdala-anterior cingulate pathway contributes to depression-like behaviors and comorbidity with chronic pain behaviors in male mice

LJ Becker, C Fillinger, R Waegaert, SH Journée… - Nature …, 2023 - nature.com
While depression and chronic pain are frequently comorbid, underlying neuronal circuits
and their psychopathological relevance remain poorly defined. Here we show in mice that …

Dual and opposing functions of the central amygdala in the modulation of pain

TD Wilson, S Valdivia, A Khan, HS Ahn, AP Adke… - Cell reports, 2019 - cell.com
Pain perception is essential for survival and can be amplified or suppressed by
expectations, experiences, and context. The neural mechanisms underlying bidirectional …

The anterior cingulate cortex is a critical hub for pain-induced depression

F Barthas, J Sellmeijer, S Hugel, E Waltisperger… - Biological …, 2015 - Elsevier
Background Besides chronic stress, chronic pain is a prevalent determinant for depression.
Changes induced in specific brain regions by sustained pain may alter the processing of …

The amygdala between sensation and affect: a role in pain

P Veinante, I Yalcin, M Barrot - Journal of molecular psychiatry, 2013 - Springer
The amygdala is a structure of the temporal lobe thought to be involved in assigning
emotional significance to environmental information and triggering adapted physiological …

Hyperactivity of anterior cingulate cortex areas 24a/24b drives chronic pain-induced anxiodepressive-like consequences

J Sellmeijer, V Mathis, S Hugel, XH Li… - Journal of …, 2018 - Soc Neuroscience
Pain associates both sensory and emotional aversive components, and often leads to
anxiety and depression when it becomes chronic. Here, we characterized, in a mouse …

Brain indoleamine 2, 3-dioxygenase contributes to the comorbidity of pain and depression

H Kim, L Chen, G Lim, B Sung, S Wang… - The Journal of …, 2012 - Am Soc Clin Investig
Pain and depression are frequently comorbid disorders, but the mechanism underlying this
association is unknown. Here, we report that brain indoleamine 2, 3-dioxygenase 1 (IDO1) …

Chronic pain–induced neuronal plasticity in the bed nucleus of the stria terminalis causes maladaptive anxiety

N Yamauchi, K Sato, K Sato, S Murakawa… - Science …, 2022 - science.org
The comorbidity of chronic pain and mental dysfunctions such as depression and anxiety
disorders has long been recognized, but the underlying mechanisms remain poorly …