Enantioselective transition metal catalysis is an area very much at the forefront of
contemporary synthetic research. The development of processes that enable the efficient …

Low molecular weight synthetic peptides have been demonstrated to be effective catalysts
for an increasingly wide array of asymmetric transformations. In many cases, these peptide …

Chiral molecules containing asymmetric carbon centers bonded with nitrogen are ubiquitous
in nature and also form important structural fragments in both natural and man-made …

Schiff base ligands are considered “privileged ligands” because they are easily prepared by
the condensation between aldehydes and imines. Stereogenic centres or other elements of …

Asymmetric catalysis has received considerable attention over the past few decades, and its
contribution toward organic synthesis has become increasingly significant. 1 A wide variety …

Catalytic asymmetric cyanations of prochiral unsaturated compounds affording the
corresponding nitrile products in high enantiomeric excess (≥ 90% in general) are …

Bifunctional α-amino nitriles are not only versatile intermediates in organic synthesis but
also exhibit a valuable dual reactivity, which has been utilized in a broad range of synthetic …

The Strecker reaction which was reported already in 1850 is the oldest known synthesis of R-
amino acids. 1 This reaction comprises a condensation of an aldehyde, ammonia, and …

The stereoselective formation of C− C bonds is of great importance for the synthesis of
enantiomerically pure natural products and pharmaceuticals. A broad repertoire of chiral …

Many enzymes are remarkable asymmetric catalysts, performing reactions effectively and
selectively. Aspiring to imitate enzymatic efficiencies, chemists have delved into Nature's …