TFAP2C promotes lung tumorigenesis and aggressiveness through miR-183-and miR-33a-mediated cell cycle regulation

J Kang, W Kim, S Lee, D Kwon, J Chun, B Son, E Kim… - Oncogene, 2017 - nature.com
Non-small cell lung cancer (NSCLC) remains one of the leading causes of death worldwide,
and thus new molecular targets need to be identified to improve treatment efficacy. Although …

Zinc finger protein 746 promotes colorectal cancer progression via c-Myc stability mediated by glycogen synthase kinase 3β and F-box and WD repeat domain …

JH Jung, DB Jung, H Kim, H Lee, SE Kang… - Oncogene, 2018 - nature.com
To elucidate the underlying oncogenic mechanism of zinc finger protein 746 (ZNF746),
current study was conducted in colorectal cancers (CRCs). Herein, ZNF746 was …

The blockage of Ras/ERK pathway augments the sensitivity of SphK1 inhibitor SKI II in human hepatoma HepG2 cells

C Zhang, H He, H Zhang, D Yu, W Zhao, Y Chen… - Biochemical and …, 2013 - Elsevier
The treatment of hepatocellular carcinoma (HCC) remains a challenge and the future of
cancer therapy will incorporate rational combinations directed to molecular targets that …

Ginkgo biloba Extract Decreases Non-Small Cell Lung Cancer Cell Migration by Downregulating Metastasis-Associated Factor Heat-Shock Protein 27

JR Tsai, PL Liu, YH Chen, SH Chou, MC Yang… - PloS one, 2014 - journals.plos.org
Heat-shock proteins (HSPs) are molecular chaperones that protect proteins from damage.
HSP27 expression is associated with cancer transformation and invasion. Ginkgo biloba …

A three-drug nanoscale drug delivery system designed for preferential lymphatic uptake for the treatment of metastatic melanoma

BS Doddapaneni, S Kyryachenko, SE Chagani… - Journal of Controlled …, 2015 - Elsevier
Metastatic melanoma has a high mortality rate due to lymphatic progression of the disease.
Current treatment is surgery followed by radiation and intravenous chemotherapy. However …

Oncogenic RAS Induces a Distinctive Form of Non-Canonical Autophagy Mediated by the P38-ULK1-PI4KB Axis

L Ge, X Wang, S Li, S Lin, Y Han, T Zhan, Z Huang… - bioRxiv, 2024 - biorxiv.org
Cancer cells with RAS mutations exhibit enhanced autophagy, essential for their
proliferation and survival, making it a potential target for therapeutic intervention. However …

EPHA2 feedback activation limits the response to PDEδ inhibition in KRAS-dependent cancer cells

Y Chen, H Lv, N Shen, X Wang, S Tang… - Acta Pharmacologica …, 2020 - nature.com
KRAS is one of the most important proto-oncogenes. Its mutations occur in almost all tumor
types, and KRAS mutant cancer is still lack of effective therapy. Prenyl-binding protein …

[PDF][PDF] Biomarqueurs des cancers colorectaux utiles en pratique clinique

AP Laurenty, J Selves, R Guimbaud - Hepato-Gastro, 2015 - fmcgastro.org
Biomarqueurs des cancers colorectaux utiles en pratique clinique Page 1 1 POST’U ( 2014
) > 1-9 Biomarqueurs des cancers colorectaux utiles en pratique clinique ; Anne-Pascale …

The involvement of liquid crystals in multichannel implanted neurostimulators, hearing and ENT infections, and cancers

C Claude-Henri, C Binot, JF Sadoc - Acta Oto-Laryngologica, 2019 - Taylor & Francis
Liquid crystals (LCs) consist of assemblies of molecules, between one and tens of
nanometers, grouped in identifiable cohorts according to orientation and structure, which is …

Signalisation cellulaire et cancer: caractérisation de cibles thérapeutiques

P de Cremoux, J Robert - Pathologie Biologie, 2012 - Elsevier
Résumé La communication cellulaire est indispensable à la vie des organismes
pluricellulaires. Les informations transmises d'une cellule à une autre correspondent à six …