Lactic acid bacteria (LAB) are important starter, commensal, or pathogenic microorganisms.
The stress physiology of LAB has been studied in depth for over 2 decades, fueled mostly by …

Bacteria encounter a myriad of stresses in their natural environments, including, for
pathogens, their hosts. These stresses elicit a variety of specific and highly regulated …

Genome‐wide screens have discovered a large set of essential genes in the opportunistic
human pathogen Streptococcus pneumoniae. However, the functions of many essential …

Lactic acid bacteria (LAB) constitute a heterogeneous group of bacteria that are traditionally
used to produce fermented foods. The industrialization of food bio-transformations increased …

The heat-shock response is a mechanism of cellular protection against sudden adverse
environmental growth conditions and results in the prompt production of various heat-shock …

Streptococcus pneumoniae (pneumococcus) kills nearly 1 million children annually, and the
emergence of antibiotic-resistant strains poses a serious threat to human health. Because …

Streptococcus pneumoniae (pneumococcus) is a leading human respiratory pathogen that
causes a variety of serious mucosal and invasive diseases. D39 is an historically important …

ABSTRACT The highly conserved WalK/WalR (also known as YycG/YycF) two-component
system is specific to low-G+ C gram-positive bacteria. While this system is essential for cell …

Clp proteolytic complexes are essential for virulence and for survival under stress conditions
in several pathogenic bacteria. Recently, a study using signature‐tagged mutagenesis …

▪ Abstract Proteolysis by cytoplasmic, energy-dependent proteases plays a critical role in
many regulatory circuits, keeping basal levels of regulatory proteins low and rapidly …