H3K9me3-heterochromatin loss at protein-coding genes enables developmental lineage specification

D Nicetto, G Donahue, T Jain, T Peng, S Sidoli… - Science, 2019 - science.org
Gene silencing by chromatin compaction is integral to establishing and maintaining cell
fates. Trimethylated histone 3 lysine 9 (H3K9me3)–marked heterochromatin is reduced in …

Rapid and accurate species identification for ecological studies and monitoring using CRISPR‐based SHERLOCK

MR Baerwald, AM Goodbla… - Molecular ecology …, 2020 - Wiley Online Library
One of the most fundamental aspects of ecological research and monitoring is accurate
species identification, but cryptic speciation and observer error can confound phenotype …

Detection of Activating Estrogen Receptor Gene (ESR1) Mutations in Single Circulating Tumor Cells

C Paolillo, Z Mu, G Rossi, MJ Schiewer, T Nguyen… - Clinical Cancer …, 2017 - AACR
Purpose: Early detection is essential for treatment plans before onset of metastatic disease.
Our purpose was to demonstrate feasibility to detect and monitor estrogen receptor 1 (ESR1) …

A 3D-printed hand-powered centrifuge for molecular biology

G Byagathvalli, A Pomerantz, S Sinha, J Standeven… - PLoS …, 2019 - journals.plos.org
The centrifuge is an essential tool for many aspects of research and medical diagnostics.
However, conventional centrifuges are often inaccessible outside of standard laboratory …

Evolutionary Dynamics of Accelerated Antiviral Resistance Development in Hypermutator Herpesvirus

T Höfler, MM Nascimento, M Zeitlow… - Molecular Biology …, 2024 - academic.oup.com
Antiviral therapy is constantly challenged by the emergence of resistant pathogens. At the
same time, experimental approaches to understand and predict resistance are limited by …

Environmental tipping points for global soil carbon fixation microorganisms

Y Hao, H Liu, J Li, L Mu, X Hu - Iscience, 2023 - cell.com
Carbon fixation microorganisms (CFMs) are important components of the soil carbon cycle.
However, the global distribution of CFMs and whether they will exceed the environmental …

Mitochondrial genetic variation and gout in Māori and Pacific people living in Aotearoa New Zealand

AL Gosling, J Boocock, N Dalbeth… - Annals of the …, 2018 - ard.bmj.com
Objective Mitochondria have an important role in the induction of the NLRP3 inflammasome
response central in gout. The objective was to test whether mitochondrial genetic variation …

[HTML][HTML] Ancient DNA of Phoenician remains indicates discontinuity in the settlement history of Ibiza

P Zalloua, CJ Collins, A Gosling, SA Biagini, B Costa… - Scientific reports, 2018 - nature.com
Ibiza was permanently settled around the 7 th century BCE by founders arriving from west
Phoenicia. The founding population grew significantly and reached its height during the 4 th …

A European mitochondrial haplotype identified in ancient Phoenician remains from Carthage, North Africa

EA Matisoo-Smith, AL Gosling, J Boocock… - PloS one, 2016 - journals.plos.org
While Phoenician culture and trade networks had a significant impact on Western
civilizations, we know little about the Phoenicians themselves. In 1994, a Punic burial crypt …

Underlying Data for Sequencing the Mitochondrial Genome with the Massively Parallel Sequencing Platform Ion Torrent PGM

SB Seo, X Zeng, JL King, BL Larue, M Assidi… - BMC genomics, 2015 - Springer
Background Massively parallel sequencing (MPS) technologies have the capacity to
sequence targeted regions or whole genomes of multiple nucleic acid samples with high …