Traumatic brain injury: progress and challenges in prevention, clinical care, and research

AIR Maas, DK Menon, GT Manley, M Abrams… - The Lancet …, 2022 - thelancet.com
Executive summary Traumatic brain injury (TBI) has the highest incidence of all common
neurological disorders, and poses a substantial public health burden. TBI is increasingly …

Post-concussion symptoms and disability in adults with mild traumatic brain injury: a systematic review and meta-analysis

C Cancelliere, L Verville, JL Stubbs, H Yu… - Journal of …, 2023 - liebertpub.com
Studies investigating long-term symptoms and disability after mild traumatic brain injury
(mTBI) have yielded mixed results. This systematic review and meta-analysis aimed to …

Association of sex and age with mild traumatic brain injury–related symptoms: a TRACK-TBI study

HS Levin, NR Temkin, J Barber, LD Nelson… - JAMA network …, 2021 - jamanetwork.com
Importance Knowledge of differences in mild traumatic brain injury (mTBI) recovery by sex
and age may inform individualized treatment of these patients. Objective To identify sex …

Incremental prognostic value of acute serum biomarkers for functional outcome after traumatic brain injury (CENTER-TBI): an observational cohort study

IRAR Helmrich, E Czeiter, K Amrein, A Büki… - The Lancet …, 2022 - thelancet.com
Background Several studies have reported an association between serum biomarker values
and functional outcome following traumatic brain injury. We aimed to examine the …

[HTML][HTML] Evidence of sex differences in cellular senescence

M Ng, LN Hazrati - Neurobiology of Aging, 2022 - Elsevier
Biological sex is a factor in many conditions, including aging, neurodegenerative disease,
cancer, and more. For each of these, men and women display distinct differences in disease …

Magnetic resonance spectroscopy of traumatic brain injury and subconcussive hits: a systematic review and meta–analysis

JM Joyce, PL La, R Walker, AD Harris - Journal of Neurotrauma, 2022 - liebertpub.com
Magnetic resonance spectroscopy (MRS) is a non-invasive technique used to study
metabolites in the brain. MRS findings in traumatic brain injury (TBI) and subconcussive hit …

Occurrence and timing of withdrawal of life-sustaining measures in traumatic brain injury patients: a CENTER-TBI study

E van Veen, M Van Der Jagt, G Citerio… - Intensive care …, 2021 - Springer
Background In patients with severe brain injury, withdrawal of life-sustaining measures
(WLSM) is common in intensive care units (ICU). WLSM constitutes a dilemma: instituting …

Exploring the social determinants of health and health disparities in traumatic brain injury: a scoping review

LW Johnson, I Diaz - Brain sciences, 2023 - mdpi.com
Traumatic brain injury (TBI) is a global health concern, that can leave lasting physical,
cognitive, and/or behavioral changes for many who sustain this type of injury. Because of the …

Longitudinal associations between persistent post-concussion symptoms and blood biomarkers of inflammation and CNS-Injury after mild traumatic brain Injury

GJB Clarke, T Skandsen, H Zetterberg… - Journal of …, 2024 - liebertpub.com
The aim of our study was to investigate the biological underpinnings of persistent post-
concussion symptoms (PPCS) at 3 months following mild traumatic brain injury (mTBI) …

Current and potential pharmacologic therapies for traumatic brain injury

J Tani, YT Wen, CJ Hu, JY Sung - Pharmaceuticals, 2022 - mdpi.com
The present article reviewed the pharmacologic therapies of traumatic brain injury (TBI),
including current and potential treatments. Pharmacologic therapies are an essential part of …