Alzheimer's disease (AD) is a multifaceted neurodegenerative condition marked by gradual
cognitive deterioration and the loss of neurons. While conventional bulk RNA sequencing …

Cancer harbours extensive proteomic heterogeneity. Inspired by the prior success of single‐
cell RNA sequencing (scRNA‐seq) in characterizing minute transcriptomics heterogeneity in …

Introduction: Cleft lip±cleft palate (CL/P) is one of the most common birth defects. Although
research has identified multiple genetic risk loci for different types of CL/P (ie, syndromic or …

Background Genomics data is available to the scientific community after publication of
research projects and can be investigated for a multitude of research questions. However, in …

The interpretation of massive high-throughput gene expression data requires computational
and biological analyses to identify statistically and biologically significant differences …

Herpes Simplex Virus type 1 (HSV-1) infects humans and causes a variety of clinical
manifestations. Many HSV-1 genomes have been sequenced with high-throughput …

Progress in sample preparation for scRNA-seq is reported based on RevGel-seq, a
reversible-hydrogel technology optimized for samples of fresh cells. Complexes of one cell …

With the advent of single-cell RNA sequencing (scRNA-seq) technology, many scRNA-seq
data have become available, providing an unprecedented opportunity to explore cellular …

We report the development and performance of a novel genomics platform, TempO-LINC, for
conducting high-throughput transcriptomic analysis on single cells and nuclei. TempO-LINC …

Cancer, a pervasive global health issue, accounts for approximately 9 million deaths
annually. The survival rate of cancer patients significantly improves with early detection and …