The wide geographic distribution of one clade of Mycobacterium tuberculosis, the Beijing
genotype family, and its genetic homogeneity, suggests that strains belonging to this …

The diverse clinico-and histopathological features, frequency of transmission and treatment
outcome of Mycobacterium tuberculosis have been associated with several environmental …

The Beijing family is the most successful genotype of Mycobacterium tuberculosis and
responsible for more than a quarter of the global tuberculosis epidemic. As the predominant …

Abstract Background Multidrug-resistant (MDR) Mycobacterium tuberculosis complex
(MTBC) strains are a serious health problem in India, also contributing to one-fourth of the …

The outcome of tuberculosis infection and disease is highly variable. This variation has been
attributed primarily to host and environmental factors, but better understanding of the global …

Existing small-animal models of tuberculosis (TB) rarely develop cavitary disease, limiting
their value for assessing the biology and dynamics of this highly important feature of human …

Abstract Background. The Mycobacterium tuberculosis Beijing strains are widespread
globally. We aimed to determine whether Beijing strains in China are more likely than other …

There have been multiple explanations put forward to try to explain the variable efficacy of
the BCG vaccine. Here I propose the new hypothesis that the primary flaw of BCG is its …

Phylogenetic analysis has shown that Beijing genotype strains can be grouped into at least
7 different sublineages. We aimed to test the hypothesis that the virulence of Beijing …

Tuberculosis (TB) has re-emerged over the past two decades: in industrialized countries in
association with immigration, and in Africa owing to the human immunodeficiency virus …