Emerging functions of circular RNA in the regulation of adipocyte metabolism and obesity

Y Zhang, Z Tian, H Ye, X Sun, H Zhang, Y Sun… - Cell Death …, 2022 - nature.com
Abstract As noncoding RNAs, circular RNAs (circRNAs) are covalently enclosed
endogenous biomolecules in eukaryotes that have tissue specificity and cell specificity …

Cross-talk between circRNAs and m6A modifications in solid tumors

F Liu, W Gu, Y Shao - Journal of Translational Medicine, 2024 - Springer
Circular RNAs (circRNAs) possess unique biological properties and distribution
characteristics that enable a variety of biological functions. N6-methyladenosine (m6A), a …

The m6A reader YTHDC1 and the RNA helicase DDX5 control the production of rhabdomyosarcoma-enriched circRNAs

D Dattilo, G Di Timoteo, A Setti, A Giuliani… - Nature …, 2023 - nature.com
Abstract N6-Methyladenosine (m6A) is well-known for controlling different processes of
linear RNA metabolism. Conversely, its role in the biogenesis and function of circular RNAs …

The circRNA circVAMP3 restricts influenza A virus replication by interfering with NP and NS1 proteins

J Min, Y Li, X Li, M Wang, H Li, Y Bi, P Xu, W Liu… - PLoS …, 2023 - journals.plos.org
Circular RNAs (circRNAs) are involved in various biological roles, including viral infection
and antiviral immune responses. To identify influenza A virus (IAV) infection-related …

M6A reduction relieves FUS-associated ALS granules

G Di Timoteo, A Giuliani, A Setti, MC Biagi… - Nature …, 2024 - nature.com
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease due to
gradual motoneurons (MN) degeneration. Among the processes associated to ALS …

An update on circular RNA in pediatric cancers

A Galardi, M Colletti, A Palma, A Di Giannatale - Biomedicines, 2022 - mdpi.com
Circular RNAs (circRNAs) are a class of single-stranded closed noncoding RNA molecules
which are formed as a result of reverse splicing of mRNAs. Despite their relative abundance …

Non-coding RNA in rhabdomyosarcoma progression and metastasis

F Ramadan, R Saab, N Hussein, P Clézardin… - Frontiers in …, 2022 - frontiersin.org
Rhabdomyosarcoma (RMS) is a soft tissue sarcoma of skeletal muscle differentiation, with a
predominant occurrence in children and adolescents. One of the major challenges facing …

CircAFF1 Is a Circular RNA with a Role in Alveolar Rhabdomyosarcoma Cell Migration

A Centrón-Broco, F Rossi, C Grelloni, R Garraffo… - Biomedicines, 2023 - mdpi.com
Circular RNAs (circRNAs), covalently closed RNAs that originate from back-splicing events,
participate in the control of several processes, including those that occur in the development …

Targeting a novel circITCH/miR-421/BTG1 axis is effective to suppress the malignant phenotypes in hepatocellular carcinoma (HCC) cells

X Li, X Yin, H Bao, C Liu - Cytotechnology, 2023 - Springer
Circular RNA-based competing endogenous RNA (ceRNA) networks contribute to the
initiation and development of various types of cancer, including hepatocellular carcinoma …

Emerging Role and Mechanism of circRNAs in Pediatric Malignant Solid Tumors

Q Shen, X Liu, W Li, X Zhao, T Li, K Zhou… - Frontiers in …, 2022 - frontiersin.org
Circular RNAs (circRNAs) are non-coding RNAs with covalent closed-loop structures and
are widely distributed in eukaryotes, conserved and stable as well as tissue-specific …