SF3B1 association with chromatin determines splicing outcomes
Much remains unknown concerning the mechanism by which the splicing machinery
pinpoints short exons within intronic sequences and how splicing factors are directed to their …
pinpoints short exons within intronic sequences and how splicing factors are directed to their …
The histone variant H2A. Bbd is enriched at sites of DNA synthesis
V Sansoni, CS Casas-Delucchi, M Rajan… - Nucleic acids …, 2014 - academic.oup.com
Histone variants play an important role in shaping the mammalian epigenome and their
aberrant expression is frequently observed in several types of cancer. However, the …
aberrant expression is frequently observed in several types of cancer. However, the …
[HTML][HTML] Differential association of chromatin proteins identifies BAF60a/SMARCD1 as a regulator of embryonic stem cell differentiation
Embryonic stem cells (ESCs) possess a distinct chromatin conformation maintained by
specialized chromatin proteins. To identify chromatin regulators in ESCs, we developed a …
specialized chromatin proteins. To identify chromatin regulators in ESCs, we developed a …
Profiling of the chromatin-associated proteome identifies HP1BP3 as a novel regulator of cell cycle progression
The chromatin-associated proteome (chromatome) regulates cellular gene expression by
restricting access of transcriptional machinery to template DNA, and dynamic re-modeling of …
restricting access of transcriptional machinery to template DNA, and dynamic re-modeling of …
Quantitative profiling of chromatome dynamics reveals a novel role for HP1BP3 in hypoxia-induced oncogenesis
In contrast to the intensely studied genetic and epigenetic changes that induce host cell
transformation to initiate tumor development, those that promote the malignant progression …
transformation to initiate tumor development, those that promote the malignant progression …
Dietary phytochemical PEITC restricts tumor development via modulation of epigenetic writers and erasers
Dietary intake of bioactive phytochemicals including the cruciferous vegetable derivative
phenethyl isothiocyanate (PEITC) can reduce risk of human cancers, but possible epigenetic …
phenethyl isothiocyanate (PEITC) can reduce risk of human cancers, but possible epigenetic …
[HTML][HTML] Cutting edge: Synchronization of IRF1, JunB, and C/EBPβ activities during TLR3–TLR7 cross-talk orchestrates Timely cytokine synergy in the proinflammatory …
Multiple pathogen-associated molecular pattern–induced TLR pathway cross-talk provokes
proinflammatory cytokine synergy in macrophages, which is important for pathogen …
proinflammatory cytokine synergy in macrophages, which is important for pathogen …
The changing chromatome as a driver of disease: a panoramic view from different methodologies
I Espejo, L Di Croce, S Aranda - BioEssays, 2020 - Wiley Online Library
Chromatin‐bound proteins underlie several fundamental cellular functions, such as control
of gene expression and the faithful transmission of genetic and epigenetic information …
of gene expression and the faithful transmission of genetic and epigenetic information …
Tousled-like kinase-dependent phosphorylation of Rad9 plays a role in cell cycle progression and G2/M checkpoint exit
R Kelly, SK Davey - PloS one, 2013 - journals.plos.org
Genomic integrity is preserved by checkpoints, which act to delay cell cycle progression in
the presence of DNA damage or replication stress. The heterotrimeric Rad9-Rad1-Hus1 (9-1 …
the presence of DNA damage or replication stress. The heterotrimeric Rad9-Rad1-Hus1 (9-1 …
Genome-wide analysis in Plasmodium falciparum reveals early and late phases of RNA polymerase II occupancy during the infectious cycle
Background Over the course of its intraerythrocytic developmental cycle (IDC), the malaria
parasite Plasmodium falciparum tightly orchestrates the rise and fall of transcript levels for …
parasite Plasmodium falciparum tightly orchestrates the rise and fall of transcript levels for …