Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins
PJ Mitchell, R Tjian - Science, 1989 - science.org
The cloning of genes encoding mammalian DNA binding transcription factors for RNA
polymerase II has provided the opportunity to analyze the structure and function of these …
polymerase II has provided the opportunity to analyze the structure and function of these …
The promiscuous life of plant NUCLEAR FACTOR Y transcription factors
The CCAAT box is one of the most common cis-elements present in eukaryotic promoters
and is bound by the transcription factor NUCLEAR FACTOR Y (NF-Y). NF-Y is composed of …
and is bound by the transcription factor NUCLEAR FACTOR Y (NF-Y). NF-Y is composed of …
Identification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional induction of mammalian glucose-regulated proteins …
H Yoshida, K Haze, H Yanagi, T Yura, K Mori - Journal of Biological …, 1998 - ASBMB
When unfolded proteins accumulate in the endoplasmic reticulum (ER), transcription of
glucose-regulated proteins (GRPs) representing ER-resident molecular chaperones is …
glucose-regulated proteins (GRPs) representing ER-resident molecular chaperones is …
Arabidopsis LEAFY COTYLEDON1 is sufficient to induce embryo development in vegetative cells
T Lotan, M Ohto, KM Yee, MAL West, R Lo, RW Kwong… - Cell, 1998 - cell.com
Abstract The Arabidopsis LEAFY COTYLEDON1 (LEC1) gene is required for the
specification of cotyledon identity and the completion of embryo maturation. We isolated the …
specification of cotyledon identity and the completion of embryo maturation. We isolated the …
[HTML][HTML] Large-scale genetic perturbations reveal regulatory networks and an abundance of gene-specific repressors
P Kemmeren, K Sameith, LAL Van De Pasch… - Cell, 2014 - cell.com
To understand regulatory systems, it would be useful to uniformly determine how different
components contribute to the expression of all other genes. We therefore monitored mRNA …
components contribute to the expression of all other genes. We therefore monitored mRNA …
Signal transduction and the control of gene expression
AH Brivanlou, JE Darnell Jr - Science, 2002 - science.org
More than 2000 transcription factors are encoded in the human genome. Such proteins have
often been classified according to common structural elements. But because transcription …
often been classified according to common structural elements. But because transcription …
CONSTANS and the CCAAT Box Binding Complex Share a Functionally Important Domain and Interact to Regulate Flowering of Arabidopsis
Abstract The CCT (for CONSTANS, CONSTANS-LIKE, TOC1) domain is found in 45
Arabidopsis thaliana proteins involved in processes such as photoperiodic flowering, light …
Arabidopsis thaliana proteins involved in processes such as photoperiodic flowering, light …
Oxygen sensing and molecular adaptation to hypoxia
HF Bunn, RO Poyton - Physiological reviews, 1996 - journals.physiology.org
This review focuses on the molecular stratagems utilized by bacteria, yeast, and mammals in
their adaptation to hypoxia. Among this broad range of organisms, changes in oxygen …
their adaptation to hypoxia. Among this broad range of organisms, changes in oxygen …
Five intermediate complexes in transcription initiation by RNA polymerase II
S Buratowski, S Hahn, L Guarente, PA Sharp - Cell, 1989 - Elsevier
A native gel electrophoresis DNA binding assay was used to resolve complexes formed on
the adenovirus Major Late Promoter by general transcription factors and RNA polymerase II …
the adenovirus Major Late Promoter by general transcription factors and RNA polymerase II …
[HTML][HTML] An iron homeostasis regulatory circuit with reciprocal roles in Candida albicans commensalism and pathogenesis
The mammalian gastrointestinal tract and bloodstream are highly disparate biological
niches that differ in concentrations of nutrients such as iron. However, some commensal …
niches that differ in concentrations of nutrients such as iron. However, some commensal …