Multiple sclerosis (MS) patients are classified as either having relapsing onset or
progressive onset disease, also known as primary progressive MS (PPMS). Relative to …

Background Primary progressive (PP) multiple sclerosis (MS) is considered a clinically
distinct entity from the spectrum of relapsing-remitting (RR) forms of the disease. Objective …

BACKGROUND: Apolipoprotein E (APOE) gene ε4, 2 alleles have been reported to be
associated with multiple sclerosis (MS), but results were conflicting. In order to derive a more …

Epidemiological studies have evaluated the association between apolipoprotein E (ApoE)
gene polymorphism and multiple sclerosis (MS) risk. However, the results remain conflicting …

BACKGROUND: Multiple sclerosis (MS) is a chronic inflammatory demyelinating disorder of
the central nervous system. Evidences linking apolipoprotein E (APOE) to myelin repair …

Abstract Background and Objectives: Apolipoprotein E (apoE) plays a central role in the
metabolism and homeostasis of lipids. ApoE gene encodes three major isoforms: ε2, ε3 and …

Abstract Aim of the Study Multiple sclerosis (MS) is a degenerative disease characterized by
autoimmune demyelination in the central nervous system. Yet, underlined genetics or …

Цель исследования. Анализ вовлеченности генов иммунного ответа в патогенезе
первично-прогрессирующего рассеянного склероза (ППРС). Материал и методы …

Рассеянный склероз является классическим мультифакториальным заболеванием, в
этиологии которого важную роль играет взаимодействие внешних факторов и …

Multiple sclerosis is a common multifactorial disease in which the etiology of the interaction
between external factors and structural specificities of a large number of genes plays an …