Staphylococcus aureus and Pseudomonas aeruginosa infectious keratitis: key bacterial mechanisms that mediate pathogenesis and emerging therapeutics

S Shah, RAF Wozniak - Frontiers in Cellular and Infection …, 2023 - frontiersin.org
Bacterial keratitis (bacterial infection of the cornea) is a major cause of vision loss
worldwide. Given the rapid and aggressive nature of the disease, immediate broad …

An update review of approaches to multiple action-based antibacterials

JB Bremner - Antibiotics, 2023 - mdpi.com
Many approaches are being pursued to address the major global health challenge posed by
the increasing resistance of pathogenic bacteria to antibacterial agents. One of the …

[HTML][HTML] Antimicrobial and antibiofilm potentiation by a triple combination of dual biocides and a phytochemical with complementary activity

S Fernandes, IB Gomes, M Simões - Food Research International, 2023 - Elsevier
The failure of current sanitation practices requires the development of effective solutions for
microbial control. Although combinations using antibiotics have been extensively studied to …

Nanobiotic Formulations utilizing Quinoline-based-Triazole functionalized Carbon Quantum Dots via Click Chemistry for Combatting Clinical-Resistant Bacterial …

N Yadav, D Mudgal, V Mishra - Indian Journal of Microbiology, 2024 - Springer
Therapeutic options for preventing the trajectory of multi-drug resistance bacterial pathogens
could rely on the effort to design a novel technique to develop a potent antimicrobial agent to …

Characteristics of Pseudomonas aeruginosa keratitis at Ho Chi Minh eye hospital

PH Nguyen, MTT Nguyen, XTT Nguyen, TT Ngo… - International …, 2025 - Springer
Background The increasing drug resistance of Pseudomonas aeruginosa (PA) poses a
serious challenge to the current treatment. Antibiograms of this pathogen often take 3-5 …

The antibiotic resistance profiles of Pseudomonas aeruginosa in the Asia Cornea Society Infectious Keratitis Study

WB Khor, R Lakshminarayanan, MH Periayah… - International …, 2024 - Springer
Purpose To describe the prevalence and antibiotic resistance profiles of Pseudomonas
aeruginosa isolated from the Asia Cornea Society Infectious Keratitis Study (ACSIKS) …

Antimicrobial Drug–Drug Interactions in the Treatment of Infectious Keratitis

E Dunster, WL Johnson, RAF Wozniak - Cornea, 2022 - journals.lww.com
Purpose: Infectious keratitis is a serious disease requiring immediate, intensive, and broad-
spectrum empiric treatment to prevent vision loss. Given the diversity of organisms that can …

Reimagining the Past: A Future for Antibiotic Drug Discovery in Ophthalmology

ER Chen, RAF Wozniak - Cornea, 2022 - journals.lww.com
Antibiotic resistance has emerged as a critical threat for the treatment of bacterial ocular
infections. To address the critical need for novel therapeutics, antibiotic drug repurposing …

Efficacy of a Novel Antibiotic Drug Combination Toward Multidrug-Resistant Ocular Pathogens

L Gowtham, RAF Wozniak, PM Dunman, E Sheba… - Cornea, 2022 - journals.lww.com
Purpose: Antimicrobial resistance is a global health threat, compounded by the reduction in
the discovery of new antibiotics. A repurposed drugs-based approach could provide a viable …