Cholangiocarcinoma (CCA) and pancreatic adenocarcinoma (PDAC) may lead to the
development of extrahepatic obstructive cholestasis. However, biliary stenoses can also be …

Metabolic profiling of biofluids is emerging as an important area with a promising number of
applications in clinical medicine, including early diagnosis of numerous diseases that …

Metabolomics is a relatively new technique that is gaining importance very rapidly. MRS-
based metabolomics, in particular, is becoming a useful tool in the study of body fluids …

Background Owing to the lack of definite diagnostic modalities, it is challenging to
distinguish malignant cases of cholangiocarcinoma (CCA), which often causes biliary tract …

Care as a legal recognition of environmental health. The Decree1 made it mandatory for the
Flemish government to perform an HBM program, which is an important policy signal of …

Objectives To demonstrate the overlap of the hepatic and bile phosphorus (31 P) magnetic
resonance (MR) spectra and provide evidence of phosphatidylcholine (PtdC) contribution to …

Human liver synthesizes bile; bile, containing a large number of metabolites, is transported
through the canaliculi and bile ducts, and stored in the gallbladder before entering into the …

High field MR scanners can resolve a metabolite resonating at 2.06 ppm in the in vivo proton‐
decoupled liver 31P MR spectrum. Traditionally this peak has been assigned to …

Prolonged biliary obstruction and infection cause retention of biliary constituents in liver
followed by hepatocyte dysfunction. Decompression therapy is important for both …

Hunting for tumoral material in body fluids, traditionally in blood, the so-called liquid biopsy
is set to revolutionize the diagnosis and management of oncological patients. However …