Transmembrane proteins comprise~ 30% of the mammalian proteome, mediating
metabolism, signalling, transport and many other functions required for cellular life. The …

The lipid raft hypothesis postulates that lipid–lipid interactions can laterally organize
biological membranes into domains of distinct structures, compositions, and functions. This …

Influenza viruses replicate within the nucleus of the host cell. This uncommon RNA virus trait
provides influenza with the advantage of access to the nuclear machinery during replication …

Cellular plasma membranes are laterally heterogeneous, featuring a variety of distinct
subcompartments that differ in their biophysical properties and composition. A large number …

Membrane lipids interact with proteins in a variety of ways, ranging from providing a stable
membrane environment for proteins to being embedded in to detailed roles in complicated …

The detailed organization of cellular membranes remains rather elusive. Based on large-
scale molecular dynamics simulations, we provide a high-resolution view of the lipid …

Biological membranes are complex and dynamic assemblies of lipids and proteins.
Poikilothermic organisms including bacteria, fungi, reptiles, and fish do not control their body …

Emerging studies increasingly demonstrate the importance of the throat and salivary glands
as sites of virus replication and transmission in early COVID-19 disease. SARS-CoV-2 is an …

It is becoming widely acknowledged that lipids play key roles in cellular function, regulating
a variety of biological processes. Lately, a subclass of glycerophospholipids, namely …

Proper membrane physiology requires maintenance of biophysical properties, which must
be buffered from external perturbations. While homeostatic adaptation of membrane fluidity …