Supramolecular luminescent sensors

TL Mako, JM Racicot, M Levine - Chemical reviews, 2018 - ACS Publications
There is great need for stand-alone luminescence-based chemosensors that exemplify
selectivity, sensitivity, and applicability and that overcome the challenges that arise from …

The strategies to cure cancer patients by eradicating cancer stem-like cells

Y Mai, J Su, C Yang, C Xia, L Fu - Molecular Cancer, 2023 - Springer
Cancer stem-like cells (CSCs), a subpopulation of cancer cells, possess remarkable
capability in proliferation, self-renewal, and differentiation. Their presence is recognized as a …

LncRNA PKMYT1AR promotes cancer stem cell maintenance in non-small cell lung cancer via activating Wnt signaling pathway

Y He, X Jiang, L Duan, Q Xiong, Y Yuan, P Liu, L Jiang… - Molecular cancer, 2021 - Springer
Background Non-small cell lung cancer (NSCLC) is the most common type of human lung
cancers, which has diverse pathological features. Although many signaling pathways and …

Concise reviews: cancer stem cell targeted therapies: toward clinical success

A Desai, Y Yan, SL Gerson - Stem cells translational medicine, 2019 - academic.oup.com
Cancer stem cells (CSCs) are a subpopulation of cells within tumors that possess the stem
cell characteristics of self-renewal, quiescence, differentiation, and the ability to recapitulate …

Targeting cancer stem cells: a strategy for effective eradication of cancer

M Shibata, MO Hoque - Cancers, 2019 - mdpi.com
Cancer stem cells (CSCs) are subpopulations of tumor cells with the ability to self-renew,
differentiate, and initiate and maintain tumor growth, and they are considered to be the main …

Triple negative breast cancer: a mountain yet to be scaled despite the triumphs

Q Wu, S Siddharth, D Sharma - Cancers, 2021 - mdpi.com
Simple Summary Triple-negative breast cancer (TNBC) is a highly aggressive subtype of
breast cancer that cannot be treated with endocrine therapy and Her2-targeted therapy …

Advances in therapeutic targeting of cancer stem cells within the tumor microenvironment: an updated review

K Dzobo, DA Senthebane, C Ganz, NE Thomford… - Cells, 2020 - mdpi.com
Despite great strides being achieved in improving cancer patients' outcomes through better
therapies and combinatorial treatment, several hurdles still remain due to therapy …

Mechanism of multidrug resistance to chemotherapy mediated by P‑glycoprotein

Y Tian, Y Lei, Y Wang, J Lai… - … Journal of Oncology, 2023 - spandidos-publications.com
Multidrug resistance (MDR) seriously limits the clinical application of chemotherapy. A
mechanism underlying MDR is the overexpression of efflux transporters associated with …

[HTML][HTML] Cancer cells stemness: A doorstep to targeted therapy

S Prasad, S Ramachandran, N Gupta, I Kaushik… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Recent advances in research on cancer have led to understand the pathogenesis of cancer
and development of new anticancer drugs. Despite of these advancements, many tumors …

Drug tolerant persister cell plasticity in cancer: A revolutionary strategy for more effective anticancer therapies

J He, Z Qiu, J Fan, X Xie, Q Sheng, X Sui - Signal transduction and …, 2024 - nature.com
Non-genetic mechanisms have recently emerged as important drivers of anticancer drug
resistance. Among these, the drug tolerant persister (DTP) cell phenotype is attracting more …