Although the memory impairment is a hallmark of Alzheimer's disease (AD), AD has also
been characterized by spatial disorientation, which is present from its early stages. Spatial …

Landmarks play an important role in guiding navigational behavior. A host of studies in the
last 15 years has demonstrated that environmental objects can act as landmarks for …

There are marked individual differences in the formation of cognitive maps both in the real
world and in virtual environments (VE; eg, Blajenkova, Motes, & Kozhevnikov, 2005; Chai & …

Several studies have pointed out that egocentric and allocentric spatial impairments are one
of the earliest manifestations of Alzheimer's Disease (AD). It is less clear how a break in the …

Older age is associated with changes in the brain, including the medial temporal lobe, which
may result in mild spatial navigation deficits, especially in allocentric navigation. The aim of …

A growing body of evidence suggests that people with Alzheimer's Disease (AD) show
compromised spatial abilities. In addition, there exists from the earliest stages of AD a …

A great effort has been made to identify crucial cognitive markers that can be used to
characterize the cognitive profile of Alzheimer's disease (AD). Because topographical …

Background Vestibular inputs have been shown to play a critical role in spatial navigation. In
this study, we sought to evaluate whether vestibular loss due to aging contributes to …

Background: Subjective cognitive complaints (SCCs) may be an early marker of prodromal
Alzheimer's disease. Objectives: Using a 10-item yes/no SCCs questionnaire (Le …

Introduction Alzheimer's disease (AD) is the leading cause of dementia worldwide, but its
pathophysiological phenomena are not fully elucidated. Many neurophysiological markers …