The association between HIV-1 Tat and Vif amino acid sequence variation, inflammation and Trp-Kyn metabolism: an exploratory investigation

ME Williams, LK Asia, Z Lindeque… - BMC Infectious …, 2024 - Springer
Background HIV-1 has well-established mechanisms to disrupt essential pathways in
people with HIV, such as inflammation and metabolism. Moreover, diversity of the amino …

A pilot investigation of the association between HIV-1 Vpr amino acid sequence diversity and the tryptophan-kynurenine pathway as a potential mechanism for …

LK Asia, EJ Van Vuren, Z Lindeque, ME Williams - Virology Journal, 2024 - Springer
HIV infection compromises both the peripheral and central immune systems due to its
pathogenic and neuropathogenic features. The mechanisms driving HIV-1 pathogenesis …