Helicobacter pylori, a member of Epsilonproteobacteria, is a Gram-negative microaerophilic
bacterium that colonizes gastric mucosa of about 50% of the human population. Although …

Helicobacter pylori is one of the main causal risk factor in the generation of chronic gastritis,
gastroduodenal ulcers and gastric carcinoma. Thus, the eradication of H. pylori infection is …

As a common kind of food, pepper is well known for its special effects on the physiological
state of human individuals. Capsaicin, the main component of pepper, is speculated to be …

Enzymes are a longstanding source of inspiration for synthetic reaction development.
However, enzymatic reactivity and selectivity are frequently untenable in a synthetic context …

Arsenosugars are a group of arsenic‐containing ribosides that are found predominantly in
marine algae but also in terrestrial organisms. It has been proposed that arsenosugar …

The radical S-adenosylmethionine (SAM) superfamily enzymes reductively cleave SAM to
produce a highly reactive 5ˊ-deoxyadenosyl (dAdo) radical, which in most cases abstracts …

Antibiotic resistance continues to spread at an alarming rate, outpacing the introduction of
new therapeutics and threatening to globally undermine health care. There is a crucial need …

Chlamydia trachomatis, an obligate intracellular bacterium with limited metabolic
capabilities, possesses the futalosine pathway for menaquinone biosynthesis. Futalosine …

MoaA is one of the most conserved radical S-adenosyl-l-methionine (SAM) enzymes, and is
found in most organisms in all three kingdoms of life. MoaA contributes to the biosynthesis of …

Aminofutalosine synthase (MqnE) is a radical SAM enzyme that catalyzes the conversion of
3-((1-carboxyvinyl) oxy) benzoic acid to aminofutalosine during the futalosine-dependent …